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Andrew Nolan, Boss Daniel, Pavel Zakharov, Michael C Mrochen; Model eye measurement with novel device combining Purkinje reflections and OLCR. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1968.
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© ARVO (1962-2015); The Authors (2016-present)
Accurate biometry measurements of the pre-op eye are important for the refractive outcomes of cataract surgery. A novel ocular biometer consisting of a Purkinje imaging method and an optical coherence device has been developed for this purpose. We hypothesise that the new ocular biometer can produce highly accurate and reproducible measurements of physical model eyes parameters.
The combination of Purkinje imaging and Optical Low Coherence Reflectometry allows measurement of the curvatures of anterior and posterior cornea, anterior and posterior lens, and internal ocular distances from anterior cornea to retina. The device was used to measure 5 model eyes with parameters representative of typical pre-operative cataract eyes.<br /> <br /> The mean radius of anterior and posterior cornea, anterior and posterior lens, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT) and axial length (AL) were measured for each model eye. These parameters had been verified by means of independent measurements. The average of the absolute value of the difference, Δ, between these two measurement methods across all measurements of all model eyes is presented. The variability for each parameter was assessed across multiple measurements of each model eye.
All parameters could be reconstructed and measured by the new ocular biometer. The differences between the parameter are below clinical relevant parameter. Table 1 show the variability across multiple measurements of each of the 5 model eyes, with the average deviation from independent measurement values.
Our results demonstrate that the new ocular biometer is capable of measuring model eyes with parameters representative of pre-op human eyes with high accuracy and repeatability. Clinical investigations are ongoing to evaluate the reproducibility of the device in human eyes.
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