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Megan Cochran, Richard W Hertle, Paul Luchette, Kajal Jassemnejad, Sandip Bhatta, Tamas Kosa, Bahman Taheri, Volodymyr Bodnar; Feasibility Study in Normal Children of a Liquid Crystal Spectacle Filter (LCSF) for Potential Treatment of Amblyopia. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2187. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate a new LCSF device applied to commercial eyeware for both comfort and the potential to reduce visual acuity
AlphaMicron Inc. Kent, Ohio, has developed a liquid crystal system designed specifically for eyewear which uses a polymer liquid crystal mixture consisting of "guest" monomers in a liquid crystal "host". This mixture is sandwiched between two curved flexible plastic substrates coated with transparent electrodes. By applying voltage to the substrates, the electro-optic response of the liquid crystal mixture is used to control the opacity of the device. The voltage is applied manually with a touch of a button or automatically through a sensor, providing instantaneous control over transmission. 20 normal children ages 7-10 were testing while wearing the LCSF. The amount of light transmission measure as a voltage was correlated to monocular and binocular visual acuity degradation using the PEDIG acuity testing paradigm.
The LCSF is successfully able to depress visual acuity in a linear fashion by changing the “haze” or light transmission function in a stepwise fashion from 20/20 to light perception.
The LCSF filter may provide multiple benefits in the treatment of, including; ease of application to commercially available eyeware, cosmetic appeal, comfort, versatility in occlusion dosage and the potential to improve adherence.
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