June 2015
Volume 56, Issue 7
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ARVO Annual Meeting Abstract  |   June 2015
Higher-order Aberrations after Posterior Chamber Phakic Intraocular lens Implantation
Hongting Liu; Jing Li; Owhofasa Agbedia; Jiangxia Wang; Xinyu Li; Hujie Wang; Lei Liu
Author Affiliations & Notes
  • Hongting Liu
    Visual science and Optometry Center, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning City, China
    Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD
  • Jing Li
    Refractive Surgery Center, Tongji Hospital of Huangzhong Science and Technology University, Wuhan, China
  • Owhofasa Agbedia
    Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD
  • Jiangxia Wang
    Biostatistics Department, School of Public Health, Johns Hopkins, Baltimore, MD
  • Xinyu Li
    Refractive Surgery Center, Tongji Hospital of Huangzhong Science and Technology University, Wuhan, China
  • Hujie Wang
    Refractive Surgery Center, Tongji Hospital of Huangzhong Science and Technology University, Wuhan, China
  • Lei Liu
    Refractive Surgery Center, Tongji Hospital of Huangzhong Science and Technology University, Wuhan, China
  • Footnotes
    Commercial Relationships Hongting Liu, None; Jing Li, None; Owhofasa Agbedia, None; Jiangxia Wang, None; Xinyu Li, None; Hujie Wang, None; Lei Liu, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 2971. doi:
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      Hongting Liu, Jing Li, Owhofasa Agbedia, Jiangxia Wang, Xinyu Li, Hujie Wang, Lei Liu; Higher-order Aberrations after Posterior Chamber Phakic Intraocular lens Implantation . Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2971.

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Abstract
 
Purpose
 

To evaluate the changes of higher-order aberrations (HOAs) after implantable collamer lenses implantations (Visian ICL; STAAR Surgical Co, Monrovia, California, USA).

 
Methods
 

In this prospective study, thirty-three eyes of 20 patients with myopia who had ICL implantation were enrolled. Before surgery and one month after surgery, the wavefront aberration data were obtained with the Hartmann-Shack wavefront sensor (KR-1W aberrometer, Topcon Corp, Tokyo, Japan). For patients with pupil size < 6 mm, the root mean square (RMS) of total ocular HOAs, RMS of third-order aberrations, RMS of fourth-order aberrations were measured and analyzed for 4 mm-pupil diameter. For patients with pupil size ≥ 6 mm, HOAs were calculated for 6 mm-pupil diameter. Visual acuity, refraction, pupil size and intra ocular pressures were also recorded.

 
Results
 

Significant improvements in visual acuities were found postoperatively, with significant reduction in spherical equivalent (P < 0.001). All HOAs in the 6 mm-pupil group were significantly higher than that of the 4 mm-pupil group, this was observed prior to and after the procedure.<br /> <br /> After one month of the implantation of ICL, the induction of total ocular HOAs, third-order aberrations, and fourth-order aberrations in 4mm-pupil group were were 0.002 ± 0.061 μm, - 0.004 ± 0.045 μm, and 0.001 ± 0.039 μm, respectively. In the 6-mm pupil group, the induction of total HOAs, third-order aberrations, and fourth-order aberrations were 0.089 ± 0.144 μm, 0.042 ± 0.117 μm, and 0.034 ± 0.060 μm, respectively. The increase in total HOAs and third-order aberrations were not statistically significant after the procedure in both groups (all P > 0.05), however, the increase in fourth-order aberrations was statistically significant in the 6mm-pupil group.

 
Conclusions
 

ICL implantation results in an improvement in visual acuity with minor increase in HOAs among eyes with 4 mm and 6 mm-pupils. Larger longitudinal studies, with a greater number of subjects are indicated to confirm these findings.  

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Table 1 and Table 2
 
Table 1 and Table 2
Table 1 and Table 2
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