June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Changes of Choroidal Thickness in Patients with Choroidal Melanoma after Ruthenium 106 Plaque Brachytherapy
Author Affiliations & Notes
  • SungChul Lee
    Ophthalmology, Yonsei University College of Medicine, Seoul, Korea (the Republic of)
  • Ji Hwan Lee
    Ophthalmology, Yonsei University College of Medicine, Seoul, Korea (the Republic of)
  • Hyesun Kim
    Ophthalmology, Yonsei University College of Medicine, Seoul, Korea (the Republic of)
  • Christopher Seungkyu Lee
    Ophthalmology, Yonsei University College of Medicine, Seoul, Korea (the Republic of)
  • Hyun Ju Park
    Ophthalmology, Yonsei University College of Medicine, Seoul, Korea (the Republic of)
  • Kyouho Lee
    Ophthalmology, Yonsei University College of Medicine, Seoul, Korea (the Republic of)
  • Jong Kyoung Na
    Ophthalmology, Yonsei University College of Medicine, Seoul, Korea (the Republic of)
  • Footnotes
    Commercial Relationships SungChul Lee, None; Ji Hwan Lee, None; Hyesun Kim, None; Christopher Seungkyu Lee, None; Hyun Ju Park, None; Kyouho Lee, None; Jong Kyoung Na, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 3437. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      SungChul Lee, Ji Hwan Lee, Hyesun Kim, Christopher Seungkyu Lee, Hyun Ju Park, Kyouho Lee, Jong Kyoung Na; Changes of Choroidal Thickness in Patients with Choroidal Melanoma after Ruthenium 106 Plaque Brachytherapy. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):3437.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose
 

To evaluate the changes of choroidal thickness before and after ruthenium (Ru)-106 plaque brachytherapy in patients with choroidal melanoma and investigate the association between choroidal thickness and tumor characteristics.<br />

 
Methods
 

Seventeen eyes of 17 patients with choroidal melanoma who were underwent Ru brachytherapy with trans-pupillary thermotherapy were reviewed retrospectively. Choroidal thickness at baseline and 6 months after brachytherapy was measured using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). The largest basal diameter (LBD) and apical height of the tumors were also measured with B-scan ultrasonography.<br />

 
Results
 

The mean subfoveal choroidal thickness in the affected eyes at baseline was 291.53 ± 46.05 ㎛, which was significantly thicker than that of unaffected fellow eyes (245.24 ± 64.34 ㎛, p=0.004). The choroidal thickness decreased significantly to 256.53 ± 62.92 ㎛ (P=0.024) at 6 months after treatment.. No significant association between the changes of choroidal thickness and the changes of ultrasonographic tumor characteristics such as LBD and apical height was found.<br />

 
Conclusions
 

The eyes with choroidal melanoma showed increased subfoveal choroidal thickness. The choroidal thickness decreased after successful treatment of local tumor therapy. Further investigation is necessary to study the implication of subfoveal choroidal thickness assessment in the management of choroidal melanoma.<br />

 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×