June 2015
Volume 56, Issue 7
ARVO Annual Meeting Abstract  |   June 2015
The Efficacy of Photodynamic Therapy for Choroidal Metastasis
Author Affiliations & Notes
  • Devon Ghodasra
    Kellogg Eye Center, University of Michigan, Ann Arbor, MI
  • Hakan Demirci
    Kellogg Eye Center, University of Michigan, Ann Arbor, MI
  • Footnotes
    Commercial Relationships Devon Ghodasra, None; Hakan Demirci, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 3443. doi:
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      Devon Ghodasra, Hakan Demirci; The Efficacy of Photodynamic Therapy for Choroidal Metastasis. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):3443.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: To evaluate the effectiveness of photodynamic therapy in the management of choroidal metastasis

Methods: Retrospective review of 12 eyes in 9 patients with choroidal metastasis

Results: Five eyes were treated with a single session of PDT, 6 eyes received 2 sessions, and 1 eye received 5 sessions. The mean preoperative ultrasound-measured tumor thickness was 1.4 mm (range, 0-2.6 mm) and mean basal diameter was 9.5 mm (range, 5-16 mm). All eyes were initially associated with subretinal fluid. At the end of a mean follow of 10.8 months (range, 2.5-42 months), 7 eyes (58%) had complete resolution of subretinal fluid while 5 eyes (42%) had improved subretinal fluid. Ten eyes (83%) had reduction of tumor thickness. The mean change in tumor thickness was -1.0 mm (mean, 1.4 to 0.4 mm). Eight eyes (67%) had stable or improved visual acuity, while 3 eyes (33%) had decreased visual acuity. Mean logMAR change in visual acuity was -0.16 (mean, 0.55 to 0.39). There were no PDT-related complications.

Conclusions: Photodynamic therapy may be a useful therapeutic option for the management of choroidal metastasis. It can be a fast and safe alternative in select cases.


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