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Devon Ghodasra, Hakan Demirci; The Efficacy of Photodynamic Therapy for Choroidal Metastasis. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):3443.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the effectiveness of photodynamic therapy in the management of choroidal metastasis
Retrospective review of 12 eyes in 9 patients with choroidal metastasis
Five eyes were treated with a single session of PDT, 6 eyes received 2 sessions, and 1 eye received 5 sessions. The mean preoperative ultrasound-measured tumor thickness was 1.4 mm (range, 0-2.6 mm) and mean basal diameter was 9.5 mm (range, 5-16 mm). All eyes were initially associated with subretinal fluid. At the end of a mean follow of 10.8 months (range, 2.5-42 months), 7 eyes (58%) had complete resolution of subretinal fluid while 5 eyes (42%) had improved subretinal fluid. Ten eyes (83%) had reduction of tumor thickness. The mean change in tumor thickness was -1.0 mm (mean, 1.4 to 0.4 mm). Eight eyes (67%) had stable or improved visual acuity, while 3 eyes (33%) had decreased visual acuity. Mean logMAR change in visual acuity was -0.16 (mean, 0.55 to 0.39). There were no PDT-related complications.
Photodynamic therapy may be a useful therapeutic option for the management of choroidal metastasis. It can be a fast and safe alternative in select cases.
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