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Daniel Diaz-Aguilar, Mayank Bansal, Mathew Farajzadeh, Irena Tsui, Steven D Schwartz, Hamid Hosseini, Jean-Pierre Hubschman; Impact of the presence of an Epi-Retinal Membrane on patients with Retinal Vein Occlusion treated with Intravitreal anti-VEGF therapy. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):3750.
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© ARVO (1962-2015); The Authors (2016-present)
To study the impact of the presence of an Epiretinal Membrane (ERM) on the visual acuity and retinal thickness after anti-VEGF therapy in patients with either Central or Branch Retinal Vein Occlusion (CRVO/BRVO).
This is a retrospective study of 140 patients with Retinal Vein Occlusion (RVO) treated with anti-VEGF therapy. Follow-up included monthly fundus and visual acuity evaluation and quarterly Optical Coherent Tomography (OCT) assessing the presence of a posterior vitreous detachment, an ERM and Macular Retinal thickness. The numbers of intra-vitreal injections as well as their frequency were monitored for each patient.
In this population of patients with RVO, the patients with an ERM demonstrated a statistically significant improvement of their functional performances after anti-VEGF therapy when compared to patients with no ERM (p< .001). The functional improvement demonstrated in patients with ERM was not related to significant change in the retinal thickness.
The presence of an ERM seems to impact favorably the functional outcomes in patients treated with anti-VEGF therapy for RVO. The presence of a vitreous detachment in most the patient with ERM may explain the favorable functional outcome.
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