June 2015
Volume 56, Issue 7
ARVO Annual Meeting Abstract  |   June 2015
Superficial corneal crosslinking during LASIK
Author Affiliations & Notes
  • Isaak Raphael Fischinger
    Ophthalmology, IROC, Zürich, Switzerland
    Opthalmology, Technische Universität München, München, Germany
  • Theo G Seiler
    Ophthalmology, IROC, Zürich, Switzerland
    Opthalmology, Technische Universität München, München, Germany
  • Tobias Koller
    Ophthalmology, IROC, Zütich, Switzerland
  • Victor Derhartunian
    Ophthalmology, IROC, Zürich, Switzerland
  • Theo Seiler
    Ophthalmology, IROC, Zürich, Switzerland
  • Footnotes
    Commercial Relationships Isaak Fischinger, None; Theo G Seiler, None; Tobias Koller, None; Victor Derhartunian, None; Theo Seiler, Wavelight Alcon (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 3936. doi:
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    • Get Citation

      Isaak Raphael Fischinger, Theo G Seiler, Tobias Koller, Victor Derhartunian, Theo Seiler; Superficial corneal crosslinking during LASIK. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):3936.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: To determine the safety of superficial corneal crosslinking (SCXL) after LASIK

Methods: In a prospective study, 78 eyes of 78 patients were treated with LASIK for myopia correction and followed for up to 1 year. All eyes had an ectasia risk score of 2 and more. After the standard LASIK (90µm-flap) a rapid CXL was performed in the interface (riboflavin 0.5% for 2 minutes, 9mW/cm2 for 5 minutes). Additional to the standard follow up-examinations at 1 and 12 months post operatively at any appointment a corneal OCT-scan was performed. The incidence of complications was statistically compared to a group of eyes treated with standard LASIK and matched regarding age, gender and attempted refractive correction.

Results: At 1 month after surgery, 5 eyes of the SCXL group had lost one line in BSCVA compared to 1 eye of the control group (p>0.05). All eyes had regained preoperative BSCVA at 1 year after surgery indicating a complication rate of less than 5%. Refractive success was identical in both groups. Early post-operative complications like erosions (15%) and DLK1 (38%) and DLK2 (5%) were significantly more frequent after SCXL.

Conclusions: Based on 1 year-results, SCXL might be considered a safe adjunct to LASIK. Whether SCXL is capable to prevent iatrogenic keratectasia is not proven.


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