June 2015
Volume 56, Issue 7
ARVO Annual Meeting Abstract  |   June 2015
Longitudinal study of retinal status using optical coherence tomography after acute post-cataract endophthalmitis
Author Affiliations & Notes
  • Thierry Zhou
    OPHTHALMOLOGY, Grenoble University Hospital, Grenoble, France
  • Catherine P Garcher
    DIJON Hospital university, Dijon, France
  • Gilles Thuret
    SAINT ETIENNE Hospital university, Saint Etienne, France
  • Alain M Bron
    DIJON Hospital university, Dijon, France
  • Florent Aptel
    OPHTHALMOLOGY, Grenoble University Hospital, Grenoble, France
  • Pierre-Loic Cornut
  • Christophe Chiquet
    OPHTHALMOLOGY, Grenoble University Hospital, Grenoble, France
  • Footnotes
    Commercial Relationships Thierry Zhou, None; Catherine Garcher, None; Gilles Thuret, None; Alain Bron, None; Florent Aptel, None; Pierre-Loic Cornut, None; Christophe Chiquet, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 4176. doi:
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      Thierry Zhou, Catherine P Garcher, Gilles Thuret, Alain M Bron, Florent Aptel, Pierre-Loic Cornut, Christophe Chiquet, FRIENDS; Longitudinal study of retinal status using optical coherence tomography after acute post-cataract endophthalmitis. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4176.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: To analyze the macular status imaged by optical coherence tomography (OCT) in patients treated for acute post-cataract endophthalmitis.

Methods: Patients presenting with an acute post-cataract endophthalmitis were included in this multicenter study from January 2008 to December 2013. Exclusion criteria were traumatic or endogenous endophthalmitis, past history of macular disease and loss of follow-up. A Time Domain (TD) or a Spectral Domain (SD) OCT was performed at each visit.

Results: 46 patients with a follow-up at month 3, 6 and 12 were included in the OCT analysis. Bacterial identification was done in 67% of cases, and virulent bacteria were identified in 13%. The prevalence of epiretinal membrane (ERM) increased during the first year of 26% to 39%, that of vitreomacular traction (VMT) decreased from 12% to 6%, and that of non-traction macular edema (ME) varied between 6.5% and 13%. Incidence of macular atrophy remained stable at 10%. At month 12, a significant correlation was found between non-tractional ME and capsular rupture during cataract extraction (p=0.03). ERM was significantly associated with an increased central macular thickness (p=0.001) and a lower VA (Mean LogMAR: 0.4 ± 0.4 versus 0.12 ± 0.2, p=0.02) at M12 in comparison to the population with normal macula. OCT analysis showed a significant association between ERM and the alteration of the ellipsoid band (p=0.02), as well as the external limiting membrane (ELM, p=0.07) at M12.

Conclusions: ERM and ME are the main macular abnormalities diagnosed one year after management of acute post-cataract endophthalmitis. Final visual acuity ≥ 20/40 was obtained in 50% of these patients. Ultrastructural abnormalities of MLE and ellipsoid band were frequently noted.


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