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Azyadeh Camacho Ordoñez, Oscar Fernandez, Elisa Dessire Alegria, Cristina Pacheco Del Valle, Regina Velasco, Oscar Baca, Alejandro Babayan; Correlation of dry eye syndrome with diabetic retinopathy, Kidney Disease Outcomes Quality Initiative and lipids panel. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4450.
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To analize the relation between dry eye syndrome (DES) with diabetic retinopathy (DR), Kidney Disease Outcomes Quality Initiative (KDOQI) and lipids panel.
Cross-sectional, prospective, observational and analytical study. We included patients of DES with DR in differents stages of the disease between july and november of 2014. Sociodemographic, clinical characteristics and laboratory studies were available for all patients. DES was measured by the Dry Eyes Work Shop, DR was staged by Early Treatment Diabetic Retinopathy Study and glomerular filtration rate (GFR) by KDOQI. Pearson correlation was used for statistical analysis.
A total of twenty-one patients were included (n=42 eyes) with a mean age of 55±8 years. Ocular Surface Disease Index mean score was 43±14, proliferative DR was present in 70% patients, stage 1 and 2 of KDOQI were the more common (80%), lipids mean score was total cholesterol 235±54, high density lipoprotein (HDL) 48±11, low-density lipoprotein (LDL) 140±48, triglycerides (TG) 179±84. Patients with higher DES had a higher relation with advanced DR (r=0.602, p=0.001), higher KDOQI stages (r=0.401, p=0.007, ), higher LDL (r=0.392, p=0.009) and lower HDL ( r=-0.338, p=0.02), total cholesterol and TG showed no significant relation.
The present study demostrate a significant relationship between DES with DR, GFR by KDOQI, LDL and HDL, therefore we recommend systematic assessment of these clinical parameters in patients with visual impairment and diabetes in order to promote opportune diagnosis and treatment.
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