Abstract
Purpose:
To investigate the effect of cataract surgery on macular ganglion cell_inner plexiform layer (mGC_IPL) thickness in glaucoma patients.
Methods:
We enrolled 95 subjects, including 14 eyes with glaucoma and 81 normal eyes. All subjects underwent cataract surgery (phacoemulsification and intraocular lens insertion) and the mGC_IPL were measured preoperatively and postoperatively (at 1 month) using a spectral-domain optical coherence tomography.
Results:
The preoperative mean mGC_IPL thickness was 68.4 ± 9.3 µm in glaucoma eyes and 75.6 ± 7.6 µm in control eyes. At one month after cataract surgery, the mean mGC_IPL were increased by 5.2 ± 1.5 µm (P < 0.001) in glaucoma eyes and by 4.3 ± 5.7 µm (P = 0.001) in control eyes. The difference between two groups were not significantly different (P = 0.550).
Conclusions:
The mGC_IPL was increased at 1 month after cataract surgery in both glaucoma and control eyes. The difference of increase in the mGC_IPL between the two groups was not significantly significant. The effect of cataract surgery on mGC_IPL thickness would be similar to glaucoma and normal eyes.