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Faruk Ozturk; Retinal nerve fiber layer and ganglion cell complex in patients with glaucoma and ocular hypertension . Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4539.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the retinal nevre fiber layer (RNFL) and ganglion cell complex (GCC) thickness in patients with primary open angle glaucoma (POAG) and ocular hypertension (OHT) and control subjects.
Twenty four eyes of 19 POAG patients, 26 eyes of 16 OHT patients and 28 eyes of 14 normal control subjects were enrolled in the study. RNFL and GCC values are measured in all.
The mean age in POAG patients was 62.4±8.4, in OHT patients was 58.7±9.5, and in controls was 49.6±6.6. RNFL values (µm) in POAG, OHT and control group, respectively, were 106.04±20.45, 110.27±15.45, 119.19±15.28 in upper quadrant, 110.21±10.11, 115.39±18.71, 128±19.12 in lower quadrant, 70.45±12.14, 82.74±20.14, 79.15±22.14 in nasal quadrant, and 65.98±25.10, 72.24±14.56, 79.32±17.14 temporal quadrant. While there was no statistically significant difference between POAG and OHT patients in any of the quadrant measurements, the measurements of superior and temporal quadrants of POAG and OHT patients were statistically significant from the control group. GCC values (µm) in POAG, OHT patients and control group, respectively, were 102.45±14.26, 110.14±20.63, 125.25±25.13 in upper temporal; 138±24.85, 130.52±32.11, 128±19.17 in upper nasal; 98.56±24.17, 101.55±12.22, 114.86±17.10 in lower temporal and 137.50±22.68, 147.33±20.77, 144.30±11.75 in lower nasal quadrants. There was no difference between the groups with respect to the quadrants.
Lower and temporal RNFL values of POAG and OHT patients were significantly lower than the values of the control group. GCC values were not significantly different between the groups.
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