June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
The Usefulness of Follow Up Mode in Glaucoma Progression Detection
Author Affiliations & Notes
  • Kenji Suda
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
  • Tadamichi Akagi
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
  • Hanako Ohashi Ikeda
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
  • Hideo Nakanishi
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
  • Kyoko Kumagai
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
  • Satoshi Morooka
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
  • Yugo Kimura
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
  • Masanori Hangai
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
    Ophthalmology, Saitama Medical University, Iruma, Japan
  • Nagahisa Yoshimura
    Ophthalmology and Visual Science, Kyoto University, Kyoto, Japan
  • Footnotes
    Commercial Relationships Kenji Suda, None; Tadamichi Akagi, None; Hanako Ikeda, None; Hideo Nakanishi, None; Kyoko Kumagai, None; Satoshi Morooka, None; Yugo Kimura, None; Masanori Hangai, None; Nagahisa Yoshimura, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 4550. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Kenji Suda, Tadamichi Akagi, Hanako Ohashi Ikeda, Hideo Nakanishi, Kyoko Kumagai, Satoshi Morooka, Yugo Kimura, Masanori Hangai, Nagahisa Yoshimura; The Usefulness of Follow Up Mode in Glaucoma Progression Detection. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4550. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: To evaluate the usefulness of the follow-up mode in detecting the glaucoma progression by measuring circumpapillary RNFL (cpRNFL) thickness in SD-OCT

Methods: The subjects were prospectively enrolled at Kyoto University Hospital from April 2008. SpectralisTM HRA+OCT system (Heidelberg Engineering, Heidelberg, Germany) were performed repeatedly. The subjects examined at least 3 times for 12 months were included in the following analysis. Linear mixed model was conducted to evaluate the longitudinal trends of the measurement.

Results: Two hundred and thirty three eyes of 149 patients were finally included in this study. One hundred and eight eyes of 62 patients (Group A, mean age ± standard deviation, 61.5 ± 10.9 years) were examined using the follow-up mode in Spectralis OCT. One hundred and twenty five eyes of 87 patients (Group B, mean age ± standard deviation, 47.1 ± 11.4 years) were examined without using the follow-up mode. Linear mixed models showed estimated average rate of global cpRNFL change per year was -1.29 μm /year in Group A (95% CI -2.00 μm/year to -0.57 μm/year) and -1.17 μm /year in Group B (95% CI -2.47 μm/year to 0.13 μm/year), suggesting that significant negative trends over time were detected in Group A but not in Group B. In sectorial analysis, significant negative trends were detected for all the sectors in Group A (-2.37 μm/year to -0.80 μm/year), but significant positive trends were detected for some sectors in Group B (-4.53 μm/year to 2.80 μm/year).

Conclusions: In evaluating the glaucoma progression by cpRNFL thickness in SD-OCT, the use of the follow-up mode may allow more accurate detection of glaucoma progression.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×