June 2015
Volume 56, Issue 7
ARVO Annual Meeting Abstract  |   June 2015
Blood Splatter During Intravitreal Injections
Author Affiliations & Notes
  • Srinivas Sai A Kondapalli
    Ophthalmology, Loyola University Health System, Maywood, IL
  • Andrew Stacey
    Ophthalmology, University of Michigan, Ann Arbor, MI
  • Felipe De Alba
    Ophthalmology, Loyola University Health System, Maywood, IL
  • Footnotes
    Commercial Relationships Srinivas Sai Kondapalli, None; Andrew Stacey, None; Felipe De Alba, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 4795. doi:
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      Srinivas Sai A Kondapalli, Andrew Stacey, Felipe De Alba; Blood Splatter During Intravitreal Injections. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4795.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: To examine the incidence of blood splatter during intravitreal injections.

Methods: One vitreoretinal specialist performed 100 consecutive intravitreal injections. After patients' eyes received anesthetic via pledgets soaked in 4% lidocaine and cleaned with betadine swabs, the specialist wore a plastic eyeshield . Once the intravitreal injection was performed, the eyeshield was removed. A new eyeshield was used for each injection. The shields were subsequently dried and stored. Each shield was sprayed with luminol a bioluminescence blood detection system. A questionnaire was provided after each injection for the vitreoretinal specialist asking if there was any intraprocedural blood splatter. One eyeshield was also placed as a control in the procedure room for 1 hour while injections were not being performed.

Results: Of the one hundred shields, seven were found to have blood splatter. On post-procedure questionnaire, the vitreoretinal specialist denied any knowledge of blood splatter. The control eyeshield was not found to have blood splatter.

Conclusions: Intraprocedureal blood splatter during intravitreal injections risks transconjunctival transmission of human immunodeficiency virus and viral hepatitis. This study is the first of its kind to document a 7% risk of blood splatter during intravitreal injections.


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