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Adriana Berezovsky, Nivea Nunes Cavascan, Joao M Furtado, Sergio Munoz, Marcos Jacob Cohen, Sung Eun Song Watanabe, Alberto Nunes Ferraz, Jacob Moyses Cohen, Rubens Belfort Jr, Solange Rios Salomao; Interobserver Agreement of Anterior Chamber Angle Measurements with Optical Coherence Tomography in Older Adults from Urban Areas of Parintins, Brazilian Amazon Region. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4981. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate inter-observer agreement of anterior chamber angle measurements using anterior segment optical coherence tomography (AS-OCT), in older adults.
The Brazilian Amazon Region Eye Survey (BARES) is a population-based prevalence study of visual impairment, blindness and ocular diseases in adults aged 45 years and older from urban and rural areas of Parintins city, Brazil. All participants are invited to a free-of-charge eye exam. Out of 1180 participants, 63 healthy subjects were selected for imaging of the nasal and temporal anterior chamber angles (ACA) of right eyes. The OCT images were analyzed offline using the iVue-100 (Optovue, Inc) software. Three masked observers graded the images independently to determine ACA (degrees) and angle opening distance (mm) at Schwalbe’s line (AOD-SL). Inter-observer agreement was qualified by using the intra-class correlation coefficient (ICC).
Mean nasal and temporal ACA were, respectively, 27.40 ± 9.10/ 31.7±10.30 for observer A, 36.4 ± 11.90/27.9±8.740 for observer B and 31.2± 10.90/29.0±7.80 for observer C. ACA measurements demonstrated excellent agreement among the three observers, with ICC=0.91 (95% Confidence Interval [CI]:0.83-0.95) for nasal and ICC = 0.90 (95% CI:0.85-0.93) for temporal quadrants. Mean nasal and temporal AOD-SL were, respectively, 356.6 ± 115.44 mm / 348.03±113.8 mm for observer A, 474.6 ± 204.2 mm /502.2±200.7 mm for observer B and 482.2± 194.5 mm /476.8±199.5 mm for observer C. For the nasal and temporal quadrants, AOD-SL measurements demonstrated good agreement among the three observers with ICC=0.79 (95% CI:0.56-0.90) and ICC=0.83 (95% CI:0.60-0.91), respectively.
The inter-observer agreement of ACA was excellent and good to AOD-SL measurements for both nasal and temporal quadrants. These results indicate that this technique provides objective documentation by different examiners in routine clinical use.
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