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Xiulan Zhang, Wenbin Huang, Xinbo Gao, Shida Chen, Jiawei Wang; Anterior and posterior ocular biometry in healthy Chinese subjects: data based on AS-OCT and SS-OCT . Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4989.
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© ARVO (1962-2015); The Authors (2016-present)
To measure the anterior and posterior of ocular biometric characteristics together and determine the relationship between iris and choroid in healthy Chinese subjects.
A total of 148 subjects (270 eyes) were enrolled in this prospective, cross-section study. The anterior and posterior of ocular biometric characteristics were measured simultaneously by anterior segment optical coherence tomography (AS-OCT) and swept-source optical coherence tomography (SS-OCT).
Compared with males, the females were with “occludable angles’’ presented with smaller anterior segment parameters (anterior chamber depth, width, area and volume (ACD, ACW, ACA, ACV), all p < 0.001), more narrow anterior chamber angle parameters (angle opening distance (AOD750), trabecular-iris space area (TISA750), angle recess area (ARA), all p < 0.001), higher iris curvature (ICURV) (p = 0.003) and larger lens vault (LV) (p = 0.019). “Occludable angles” were correlated with increasing age (P < 0.01). Iris thickness (IT750) and iris area (IAREA) was found associated with age, ACW, and pupil diameter (all p < 0.05), while choroidal thickness (CT) was associated with age, gender, and axial length (all p < 0.05). In univariate regression analysis, greater CT was significantly associated with smaller IAREA (p = 0.026).
Compared with male eyes, female eyes had “occludable angles’’ that correlated with increasing age, which would be helpful in explaining the higher prevalence of angle closure rates in the female gender and aging people. Greater CT might associate with smaller iris area; however, it needs to be investigated in a future study to reach a precise conclusion.<br /> <br /> Supports: The National Natural Science Foundation of China (81170849, 81371008).
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