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Shan C Lin, Roland Y Lee, Shuai-Chun Lin, Rebecca I Chen, Diego Tebaldi de Queiroz Barbosa; Associations between Trabecular Meshwork Length, Intraocular Pressure, and Anterior Chamber Angle Width.. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):4995.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the associations between trabecular meshwork length, intraocular pressure, and anterior chamber angle width using spectral domain anterior segment optical coherence tomography.
In this prospective study, spectral domain anterior segment optical coherence tomography images were analyzed to determine trabecular meshwork length and three anterior chamber angle width parameters measured at different distances from the scleral spur: angle opening distance at 250, 500, and 750 mm from the scleral spur (AOD250, AOD500, AOD750); trabecular-iris space area at 500 and 750 mm from the scleral spur (TISA500, TISA750); angle recess area at 750 mm from the scleral spur (ARA750). Intraocular pressure was obtained by Goldmann applanation tonometry. Linear regression models were used to evaluate the associations between trabecular meshwork length, intraocular pressure, and anterior chamber angle width parameters.
Three hundred and thirteen eyes from 176 nonglaucomatous patients were analyzed. Our linear regression analyses showed a significant negative association between trabecular meshwork length and intraocular pressure (P=0.003), and a significant positive association between trabecular meshwork length and all anterior chamber angle width parameters (all P<0.05).
Our results showed that greater trabecular meshwork length is associated with lower intraocular pressure, and eyes with wider anterior chamber angle tended to have greater trabecular meshwork length.
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