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Daniel Rangel-O'Shea, Pablo Jose Guzman-Salas, Miriam Guadalupe Arellano-Ganem, Miguel Pedroza-Seres; Epidemiological characteristics of Vogt-Koyanagi-Harada syndrome in a mexican population. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):5770.
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© ARVO (1962-2015); The Authors (2016-present)
Report the number of patients with Vogt-Koyanagi-Harada syndrome attending a Uveitis Department and analyze different epidemiological characteristics of this disease.
Retrospective case series study in an uveitis department with 103 patients with Vogt-Koyanagi-Harada syndrome from 2001 to 2013. We reviewed medical records from patients at Instituto de Oftalmologia “Conde de Valenciana“ in Mexico. We collected information of: gender, age, visual acuity -before and after treatment-, ocular manifestations, neurological signs, auditory signs, cutaneous changes, number of inflammatory episodes and diagnosis criteria.
We analyzed 103 patients, with average age of 37.71±12.76 years, with 80 females and 23 males.<br /> Average inicial visual acuity was 0.96±1.01 logMAR on right eye and 0.92±0.93 logMAon left eye, Average final visual acuity was 0.48±0.63 logMAR on right eye and 0.55±0.77 logMAR on left eye.Final visual acuity improved on 79 patients after treatment. Number of acute episodes were diferent on patients, 30 patients had only 1 episode of inflamation, 32 patients had two episodes, 23 patients had 3 episodes and 18 patients has more than three episodes. Ocular findings were variable, 44(42.71%) patients showed serous retinal detachment, 38 (36.89%) patients showed macular edema, 85 (82.52%)patients showed sunset fundus, 66 (64.07%) showed optic disc swelling, 21 (20.38%) showed cutaneous changes, 31 (30.09%) had auditory signs and 37 (35.92%) had neurological signs. 27 ( 26.21%) patients had criteria for probale VKH, 9 (8.73%) for incomplete VKH and 4 (3.88%) for complete VKH.
This is the first study in Mexico, with this number of patients, describing VKH epidemiologic data.<br /> The information obtained help us to understand better this patology in mexican population and could predict future clinical course.
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