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Roberto Dell'Omo, Mariaelena Filippelli, Dario Giorgio, Roberto Di Iorio, Ermanno dell'Omo, Ciro Costagliola; Restoration of foveal thickness and architecture after macula-off retinal detachment repair.. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):5906.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the foveal changes after repair of macula-off rhegmatogenous retinal detachment (RRD).
Prospective comparative case series. Twenty-four eyes of 24 patients with macula-off/ fovea-on detachment ( n= 9) and fovea-off detachment (n=15) were studied. Serial optical coherence tomography (OCT) images taken at the same location were recorded at month 1,3,6 and 12 after operation. Fellow eyes were used as controls.
No significant changes of the central foveal thickness (CFT) were recorded in the fovea-on group over the follow-up. From month 1 to month 12, CFT increased significantly in the fovea-off group (P< 0.001). In this group, a significant increase of the Henle fiber and outer nuclear layer thickness(P=0.004), and of the ellipsoid zone (EZ)-retinal pigment epithelium (RPE) thickness (P < 0.001) was recorded. Significant restoration of the integrity of the external limiting membrane in the fovea-off group (P <0.001) and significant restoration of the EZ and cone interdigitation zone in the fovea-on group and the fovea-off group were observed (P <0.02 and P<0.001, and P<0.00 and P<0.001, respectively). Twelve months after operation the foveal bulge restored in 8 out of 15 eyes of the fovea-off group.
OCT scans taken serially at the same location show a progressive increase of foveal thickness and restoration of the integrity of outer retinal bands after repair of fovea-off RRD. The ELM-RPE thickness correlates with BCVA.
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