June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
MACULAR THICKNESS MEASURED BY OPTICAL COHERENCE TOMOGRAPHY IN HEALTHY OLDER ADULTS FROM THE CITY OF PARINTINS, BRAZILIAN AMAZON REGION
Author Affiliations & Notes
  • Sung Eun Song Watanabe
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Paula Y Sacai
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Nivea Nunes Cavascan
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Marcela Cypel
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Sergio Munoz
    Salud Publica, Universidad de La Frontera, Temuco, Chile
  • Paulo Henrique Avila Morales
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Jacob Moyses Cohen
    Instituto de Olhos de Manaus, Manaus, Brazil
    Divisão de Oftalmologia, Depto. de Cirurgia, Universidade Federal do Amazonas, Manaus, Brazil
  • Adriana Berezovsky
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Rubens Belfort Jr
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Solange Rios Salomao
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Footnotes
    Commercial Relationships Sung Watanabe, None; Paula Sacai, None; Nivea Cavascan, None; Marcela Cypel, None; Sergio Munoz, None; Paulo Henrique Morales, None; Jacob Cohen, None; Adriana Berezovsky, None; Rubens Belfort Jr, None; Solange Salomao, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 593. doi:https://doi.org/
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      Sung Eun Song Watanabe, Paula Y Sacai, Nivea Nunes Cavascan, Marcela Cypel, Sergio Munoz, Paulo Henrique Avila Morales, Jacob Moyses Cohen, Adriana Berezovsky, Rubens Belfort Jr, Solange Rios Salomao; MACULAR THICKNESS MEASURED BY OPTICAL COHERENCE TOMOGRAPHY IN HEALTHY OLDER ADULTS FROM THE CITY OF PARINTINS, BRAZILIAN AMAZON REGION. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):593. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To provide normative values of macular thickness in a subset of participants of a population-based ocular eye survey using SD-OCT.

Methods: The Brazilian Amazon Region Eye Survey (BARES) is an ongoing cross-sectional population-based study to determine prevalence and causes of visual impairment, blindness and ocular diseases in adults aged 45 years and older in urban and rural areas of the city of Parintins. Sixty-four eyes of 64 healthy normal subjects (28 males), aging from 45-65 (mean= 52±5) had a comprehensive ophthalmic exam. All selected participants had best corrected visual acuity ≥ 20/32, normal eye exam and no prior ocular surgery. OCT was performed using standard scanning protocols and retinal full thickness in Early Treatment Diabetic Retinopathy Study (ETDRS) subfields was assessed. Retinal thickness was calculated for 9 subfields from the inner and outer retinal boundaries. The associations between thickness measurements with age, gender, refractive errors and schooling level were investigated. Statistical significance was established at ≤0.05.

Results: The average central foveal thickness was 252.3±19.2µm. Age was negatively correlated with macular thickness in the following areas: inner foveal layer (p=0.020); inner nasal (p=0.004) and inferior (p=0.002) parafovea; outer layer of nasal (p=0.016), superior (p=0.000) and inferior (p=0.045) parafovea; nasal (p=0.001) and superior (p=0.026) perifovea. Macular thickness showed to be larger in males in the following areas: temporal parafoveal total thickness (p=0.0198), temporal inner parafoveal (p=0.0058) and nasal outer parafoveal (p=0.033). There was no relationship between macular thickness and spherical equivalent. The data suggested a negative correlation between schooling educational level and decrease in retina thickness for inner (p=0.020) and outer foveal areas (p=0.000).

Conclusions: The current results provide a normative database of macular thickness in healthy Brazilian Amazon population using SD-OCT. We suggest that age should be considered while interpreting the retina thickness. These parameters will be useful to characterize retinal disorders in future studies in this population.

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