June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Wide-field schematic model of the Human Eye with Asymmetrically Tilted and Decentered Lens
Author Affiliations & Notes
  • James Polans
    Biomedical Engineering, Duke University, Durham, NC
  • Bart Jaeken
    R&D, VOPTICA SL, Murcia, Spain
  • Ryan P McNabb
    Biomedical Engineering, Duke University, Durham, NC
    Ophthalmology, Duke University, Durham, NC
  • Lucia Hervella
    R&D, VOPTICA SL, Murcia, Spain
  • Pablo Artal
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Joseph A Izatt
    Biomedical Engineering, Duke University, Durham, NC
    Ophthalmology, Duke University, Durham, NC
  • Footnotes
    Commercial Relationships James Polans, None; Bart Jaeken, Voptica (E); Ryan McNabb, None; Lucia Hervella, Voptica (E); Pablo Artal, Voptica (I), Voptica (P), Voptica (S); Joseph Izatt, Bioptigen Inc (I), Bioptigen Inc (P), Bioptigen Inc (S)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 6019. doi:
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      James Polans, Bart Jaeken, Ryan P McNabb, Lucia Hervella, Pablo Artal, Joseph A Izatt; Wide-field schematic model of the Human Eye with Asymmetrically Tilted and Decentered Lens. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):6019.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

More accurate schematic eye models would aid in the design of advanced ophthalmic instrumentation, including OCT, SLO, fundus cameras and fluorescence imagers. Since the aberrations of the human eye vary strongly with retinal eccentricity, it becomes increasingly important to have an optically accurate eye model for the design of instruments requiring a wide field-of-view. We propose a schematic eye that reproduces the aberrations of the human eye across a wide visual field.

 
Methods
 

The model eye was built to reproduce the experimentally measured wavefront aberrations for 4-mm pupil recorded for the central 80° of the horizontal meridian (101 eyes) and 50° of the vertical meridian (10 eyes). These data were acquired using a custom scanning Shack-Hartmann wavefront sensor [1]. Optical modeling software (Zemax) and a reverse building eye modeling technique were used to optimize a merit function. We developed a custom surface in order to allow the model to be more easily incorporated into the design of imaging instruments.

 
Results
 

Across the entire field-of-view, the eye model shows excellent agreement with the measured data both comprehensively and for low-order and high-order aberrations (Fig. 1). In comparison to previous eye models (Fig. 2), our schematic eye excels at reproducing the aberrations at the peripheral retinal. Tilt and decentration of the crystalline lens permits our model to mimic the asymmetries of the aberrations found in real eyes.

 
Conclusions
 

Our proposed model shows great promise towards the design of wide-field imaging instruments, and it has the potential to provide further insights in the study of the peripheral optics of the human eye. Also, we outline a robust eye modeling technique that is capable of predicting trends beyond those defined explicitly in the optimization routine.<br /> 1. B. Jaeken, L. Lundstrom, and P. Artal, Opt Express 19, 7903 (2011).  

 
2D grid of measured wavefront data (left) compared with the aberrations calculated for the newly proposed eye model (right) in the pupil plane.
 
2D grid of measured wavefront data (left) compared with the aberrations calculated for the newly proposed eye model (right) in the pupil plane.
 
 
Plots showing Zernike aberrations versus retinal eccentricity across the horizontal meridian: oblique astigmatism (a), defocus (b), vertical astigmatism (c), horizontal coma (d), oblique trefoil (e), spherical aberration (f), mean sphere (g), and cylinder (h). Error bars correspond to the standard deviation in the measured data (101 eyes).
 
Plots showing Zernike aberrations versus retinal eccentricity across the horizontal meridian: oblique astigmatism (a), defocus (b), vertical astigmatism (c), horizontal coma (d), oblique trefoil (e), spherical aberration (f), mean sphere (g), and cylinder (h). Error bars correspond to the standard deviation in the measured data (101 eyes).

 
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