June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Relationship between Maternal Race/Ethnicity and Retinopathy of Prematurity in a Colorado Cohort
Author Affiliations & Notes
  • Emily A McCourt
    Ophthalmology, University of Colorado, Aurora, CO
    Children's Hospital Colorado, Aurora, CO
  • Yu Cheol Kim
    Ophthalmology, University of Colorado, Aurora, CO
    Ophthalmology, Keimyung University School of Medicine, Daegu, Korea (the Republic of)
  • Ashlee Cerda
    Ophthalmology, University of Colorado, Aurora, CO
  • Jasleen Singh
    Ophthalmology, University of Colorado, Aurora, CO
    Children's Hospital Colorado, Aurora, CO
  • Brandie D Wagner
    Ophthalmology, University of Colorado, Aurora, CO
  • Jennifer Jung
    Ophthalmology, University of Colorado, Aurora, CO
    Children's Hospital Colorado, Aurora, CO
  • Jennifer Cao
    Ophthalmology, University of Colorado, Aurora, CO
  • Rebecca Sands Braverman
    Ophthalmology, University of Colorado, Aurora, CO
    Children's Hospital Colorado, Aurora, CO
  • Robert Enzenauer
    Ophthalmology, University of Colorado, Aurora, CO
    Children's Hospital Colorado, Aurora, CO
  • Anne Lynch
    Ophthalmology, University of Colorado, Aurora, CO
  • Footnotes
    Commercial Relationships Emily McCourt, None; Yu Cheol Kim, None; Ashlee Cerda, None; Jasleen Singh, None; Brandie Wagner, None; Jennifer Jung, None; Jennifer Cao, None; Rebecca Braverman, None; Robert Enzenauer, None; Anne Lynch, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 949. doi:https://doi.org/
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    • Get Citation

      Emily A McCourt, Yu Cheol Kim, Ashlee Cerda, Jasleen Singh, Brandie D Wagner, Jennifer Jung, Jennifer Cao, Rebecca Sands Braverman, Robert Enzenauer, Anne Lynch; Relationship between Maternal Race/Ethnicity and Retinopathy of Prematurity in a Colorado Cohort. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):949. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To determine the incidence of high grade Retinopathy of Prematurity (Type 1 or Type 2) in babies born to women from different racial and ethnic groups in a contemporary cohort (2008 to 2012) at two tertiary care neonatal intensive care units (University of Colorado Hospital and Children’s Hospital Colorado).

Methods: We performed a retrospective cohort study on the records of 650 newborns who underwent Retinopathy of Prematurity (ROP) screening using the 2013 screening criteria (gestational age at delivery less than 31 weeks’ gestation or birth weight ≤ 1500 grams). We excluded: Low grade ROP (n = 116) and other or uncertain race/ethnicity (n=150). We examined the incidence of ROP across race/ethnicity (non-Hispanic White, Hispanic, African American, and Asian).

Results: In the analytic dataset (n = 384), there were 56 (14.6%) newborns who developed high grade ROP. The number of babies with high grade ROP born to Asian, Non-Hispanic White, Hispanic and African American women was 2/12 (16.67%), 32/197 (16.24%), 22/134 (16.42%), and 0/41 (0%) respectively (P =.05). We found a significant difference in the mean gestational age (weeks) at delivery (P=.01) and mean birth weight (grams) between the groups (P=.03). The gestational ages at delivery (mean ± SD) across the groups were: non-Hispanic White (28.6 ± 2.4), Hispanic (28.4 ± 2.4), African American (29.6 ± 1.7), and Asian (27.6 ± 2.4). The birth weights (mean ± SD) across the groups were: non-Hispanic White (1154 ± 353.2), Hispanic (1213 ± 392.5), African American (1316 ± 299.7), and Asian (1056 ± 339.7).

Conclusions: We found no case of high grade ROP among neonates born to African American women. These neonates had the highest mean gestational age and birth weight at delivery. In contrast, newborns of Asian women had a similar incidence of ROP compared to babies born to non-Hispanic White and Hispanic women, yet had the lowest observed mean birth weight and gestational age at delivery. We show that the incidence of ROP is different amongst racial groups. These interesting observations need further exploration in a larger cohort.

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