Abstract
Purpose:
to study structural changes of fundus in children with a history of retinopathy of prematurity (ROP) using transversal spectral-domain optical coherence tomography (OCT).
Methods:
We examined 22 children (27 eyes) with regressive ROP aged from 3 to 15 (10±4,5) years. In addition to the traditional ophthalmic examination all patients underwent transversal OCT (Spectralis HRA+OCT, Heidelberg Engineering, Germany).
Results:
Ophthalmoscopic examination revealed following changes: avascular regions (27 eyes, 100%), shift of vascular bundle and tractional ONH deformation (27 eyes, 100%), extraretinal tissue (15 eyes, 55%), local retinal detachment (5 eyes, 19%).<br /> Using transversal OCT we revealed epiretinal membrane, located in macular zone in 24 eyes (89%), peripapillar zone - 11 eyes (41%), in the course of retinal vessels - 6 eyes (22%). We discovered polymorphic focuses of reduced reflectivity of RPE and outer segments of photoreceptors. These focuses were located in macular zone in 19 eyes (70%), in peripapillar zone - 11 eyes (41%), in the course of retinal vessels - 6 eyes (22%). We found the following changes of choriocapillar layer: local hyperreflectivity in submacular region - 17 eyes (63%), diffuse hyperreflectivity of entire scaned area - 4 eyes (15%), substitution of choriocapillars by medium and large choroidal vessels - 5 eyes (19%).
Conclusions:
This study demonstrates the role of transversal OCT in diagnostics of structural changes of fundus in children with ROP and substantiates further research in this direction.