March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Inter- and Intraobserver Variability of Measurements with Pentacam HR® in Patients with Mild to Moderate Keratoconus
Author Affiliations & Notes
  • Ivo Guber
    Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland
  • Kate Hashemi
    Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland
  • Andreas Schötzau
    Department of Ophthalmology, University Hospital of Basel, Basel, Switzerland
  • Josef Guber
    Department of Ophthalmology, University Hospital of Basel, Basel, Switzerland
  • François Majo
    Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland
  • Footnotes
    Commercial Relationships  Ivo Guber, None; Kate Hashemi, None; Andreas Schötzau, None; Josef Guber, None; François Majo, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 113. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Ivo Guber, Kate Hashemi, Andreas Schötzau, Josef Guber, François Majo; Inter- and Intraobserver Variability of Measurements with Pentacam HR® in Patients with Mild to Moderate Keratoconus. Invest. Ophthalmol. Vis. Sci. 2012;53(14):113. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose:
 

To evaluate inter- and intraobserver variability of indices crucial for detection of keratoconus progression derived from the Pentacam HR® (high-resolution) tomographer (OCULUS Optikgeräte GmbH, Wetzlar, Germany) in patients with mild to moderate keratoconus.

 
Methods:
 

Three repeated corneal topography measurements in the 25-picture mode by two independent observers were performed. The extent of variability across a large range of measurement parameters was analyzed including anterior and posterior corneal surface measurements, pachymetry values, corneal volume, anterior chamber volume and depth, and iridocorneal angle. The intraclass correlation coefficient (ICC) between and within each investigator was calculated to assess reproducibility and repeatability, respectively.

 
Results:
 

31 eyes of 20 patients (mean age 31.6, SD ± 8.6) were included. Overall, the repeatability and reproducibility were excellent. The range of variability was reported by calculating the standard deviation of measurements. The detailed results are shown in Table 1.

 
Conclusions:
 

This study shows that the Pentacam HR® tomographer provides reliable measurements in patients with mild to moderate keratoconus. However, all parameters showed a certain range of variability. This should be taken into account when assessing keratoconus progression in order to distinguish true progression from variability in measurements. In addition, the excellent reproducibility suggests that the measurements can be reliably performed by different individuals from one visit to another.  

 
Keywords: keratoconus • refractive surgery: corneal topography • cornea: clinical science 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×