March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
Reproducibility Of Rotating Scheimpflug Camera Imaging System In Patients With Keratoconus
Author Affiliations & Notes
  • Barbara Sala
    Medicine, Surgery, Eye Clinic, Milan, Italy
  • Paolo Fogagnolo
    G.B. Bietti Foundation IRCCS Rome, Rome, Italy
  • Maurizio Diguini
    Medicine, Surgery, Eye Clinic, Milan, Italy
  • Laura Ottobelli
    Medicine, Surgery, Eye Clinic, Milan, Italy
  • Luca Maria Rossetti
    Medicine, Surgery, Eye Clinic, Milan, Italy
  • Footnotes
    Commercial Relationships  Barbara Sala, None; Paolo Fogagnolo, None; Maurizio Diguini, None; Laura Ottobelli, None; Luca Maria Rossetti, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 130. doi:
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    • Get Citation

      Barbara Sala, Paolo Fogagnolo, Maurizio Diguini, Laura Ottobelli, Luca Maria Rossetti; Reproducibility Of Rotating Scheimpflug Camera Imaging System In Patients With Keratoconus. Invest. Ophthalmol. Vis. Sci. 2012;53(14):130.

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      © ARVO (1962-2015); The Authors (2016-present)

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To determine the reproducibility of indices for diagnosis and follow-up of keratoconus measured with Rotating Scheimpflug Camera imaging system (Pentacam).


Three consecutive scans, taken by the same operator, at a 5 minute interval each, were randomly taken on one eye of 14 patients with keratoconus using Pentacam. The parameters taken into evaluation were: corneal volume (CV), maximal keratometry value (K max), radii of curvature (Rh, Rv) and mean keratometry (Rm) of front (CF) and back (CB) cornea, thinnest location (TL), x (X) and y (Y) position of TL, anterior (ACE) and posterior corneal elevation (PCE) of TL.Reproducibility was assessed by calculating percentage coefficient of variation (%CoV) for all parameters except X and Y for which standard deviation (SD) was considered. The effect of mean value on %CoV was tested by regression analysis and their association with R2.


Results are shown in Table 1. %CoVs were <2% in all parameters except ACE and PCE (about 5% each). SD was 0.05 for X and 0.31 for Y. Regression analysis was negative and R2 negligible for all parameters except for RmCF (y= -0,2811x +2,3185, P=0.007, R2=0.47)


Pentacam %CoVs in patients with keratoconus were low and independent from mean values (except RmCF). Values outside these ranges should be considered suspect for progression of the disease.  

Keywords: keratoconus • imaging/image analysis: clinical 

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