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Lucia Tanga, Francesco Oddone, Gianluca Manni, Manuela Ferrazza, Francesca Berardo, Paolo Fogagnolo, Marco Centofanti; Learning Effect of Flicker Defined Form Perimetry in ocular hypertensive patients. Invest. Ophthalmol. Vis. Sci. 2012;53(14):185.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the learning effect of ocular hypertensive patients at flicker defined form perimetry (FDF) as performed by the Heidelberg Hedge Perimeter (Heidelberg Engineering, Germany)
patients with ocular hypertension and with healthy optic nerve and normal visual field were enrolled and performed 5 repetitions of ASTA-Standard 24-2 FDF test at intervals of 7±2 days in one eye. Learning effect was defined as an improvement over the repetitions of duration, perimetric indices, mean total sensitivity and mean sensitivity at different eccentricities Glaucoma Hemifield Test (GHT), or number of points with a P < 5% and < 1% in the total and pattern deviation maps. Improvement over repetitions was evaluated by means of one-way analysis of variance (ANOVA) for repeated measures. For parameters with statistically significant ANOVA, matched paired ttest (α=0.05) was used to detect interexamination differences. For categorical variables Χ2 test was used. In case of statistically significant learning effect, correlations with demographic and biometric parameters was explored by means of Pearson’s correlation coefficient.
20 ocular hypertensive patients were enrolled. Mean test duration changed from 430.0±102.71 sec to 394.7±65.7 sec (p=0.63). Mean total sensitivity changed progressively over the 5 repetitions from 17.1±3.0 dB to 18.1±2.6 dB and this change was not statistically significant (p= 0.77). A similar beaviour was found also for central, paracentral and peripheral mean sensitivity. MD changed from -2.24±3.0 dB at the first repetition to -1.14±2.8 dB at the fifth repetition and this change was not statistically significant (p=0.76). PSD changed from 2.34±0.9 dB to 2.33±1.0 dB from the first to the fifth repetition and this change was not statistically significant (p=0.77). GHT was within normal limits in 60% of patients at the first and second repetitions, in 50% of patients at the third repetition, in 60% of patients at the fourth repetition and in 75% of patients at the last repetition and these fluctuations were not statistically significant. Mean number of points with p<5% in the total deviation map reduced from 9.5±11.7 to 6.3±8.5 over the 5 test repetitions (p=0.8). Mean number of points with p<1% in the total deviation map reduced from 4.8±7.7 to 2.6±5.1 over the 5 test repetitions (p=0.84). Mean number of points with p<5% in the pattern deviation map reduced from 6.4±5.0 to 6.3±4.6 over the 5 test repetitions (p=0.88). Mean number of points with p<1% in the pattern deviation map reduced from 2.8±3.7 to 2.1±3.4 over the 5 test repetitions (p=0.68).
ASTA-Standard 24-2 FDF test is not affected by learning effect in ocular hypertensive patients previously exposed to standard acromatic perimetry.
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