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Michael Haustein, Kathleen Wozniak, Eberhard Spoerl, Lutz E. Pillunat; Comparative Measurements Of Pachymetry By The Anterior Segment Module (ASM) Of Spectralis-OCT And By Ultrasound, SL-OCTAnd Pentacam. Invest. Ophthalmol. Vis. Sci. 2012;53(14):98.
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© ARVO (1962-2015); The Authors (2016-present)
To compare central corneal thickness (CCT) by ASM and 3 other pachymetry devices: SL-OCT, Pentacam and Tomey ultrasound-pachymetry. CCT measurements were correlated to anterior camber depth and curvature.
142 eyes of 71 normal subjects were included in this prospective, cross- sectional observational study. Three central corneal thickness measurements were randomly performed by SL-OCT, by ASM and Pentacam. Ultrasound measurements were taken at last. The statistical analyses were done by SPSS®. For comparison the mean values, the intraclass correlation coefficients (ICC) and the Bland-Altman-plots were used.
Mean CCT by ASM, SL-OCT, Pentacam, and Tomey SP3000 was 550.65±37.05 µm, 542.58±38.06 µm, 544.5±38.37 µm, and 548.97±46.27µm, respectively. The difference and the ICC between ASM-SLOCT was -7.5±21.8 µm (P=0.007), ICC = 0.820, between ASM-Tomey -1.19±24.9 µm (P=0.694), ICC=0.819, and between ASM-Pentacam -7.0±21.2 µm (P=0.007), ICC=0.824.ASM CCT was not significantly different from CCT measured by ultrasound pachymetry. In contrast, the other two non contact devices measured slightly thinner than ASM (P<0.007). There were no statistically significant correlations to anterior camber depth and corneal curvature.
The AMS provides sufficient CCT and the results are comparable to other pachymetric devices, like SL-OCT, Pentacam, and Tomey SP3000. Differences in CCT between the four devices are not clinically relevant. Therefore, all used measurement devices are interchangeable.
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