March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
Correlation Of Ocular Perfusion Pressure And Ocular Pulse Amplitude In Glaucoma, Ocular Hypertensive And Normal Individuals
Author Affiliations & Notes
  • Fabio N. Kanadani
    Ophthalmology/Glaucoma, New York Eye and Ear Infirmary, Belo Horizonte, Brazil
  • Bruno P. Figueiredo
    Ophthalmology/Glaucoma, hospital Sao Geraldo, Belo Horizonte, Brazil
    University Federal of Minas Gerais, Belo Horizonte, Brazil
  • Sebastiao Cronemberger
    Ophthalmology, Federal Univ of Minas Gerais, Belo Horizonte, Brazil
  • Carlos R. Figueiredo
    Ophthalmology/Glaucoma, IMOL, Belo Horizonte, Brazil
  • Tereza C. Kanadani
    Ophthalmology/Glaucoma, Hospital Universitário São José, Belo Horizonte, Brazil
  • Syril Dorairaj
    Glaucoma, Hamilton Glaucoma Center and Department of Ophtalmology, New York, New York
  • Nubia V. Lima
    University Federal of Minas Gerais, Belo Horizonte, Brazil
  • Footnotes
    Commercial Relationships  Fabio N. Kanadani, None; Bruno P. Figueiredo, None; Sebastiao Cronemberger, None; Carlos R. Figueiredo, None; Tereza C. Kanadani, None; Syril Dorairaj, None; Nubia V. Lima, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 243. doi:
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      Fabio N. Kanadani, Bruno P. Figueiredo, Sebastiao Cronemberger, Carlos R. Figueiredo, Tereza C. Kanadani, Syril Dorairaj, Nubia V. Lima; Correlation Of Ocular Perfusion Pressure And Ocular Pulse Amplitude In Glaucoma, Ocular Hypertensive And Normal Individuals. Invest. Ophthalmol. Vis. Sci. 2012;53(14):243.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To investigate a possible correlation between ocular perfusion pressure (OPP) and ocular pulse amplitude (OPA) in individuals with glaucoma, ocular hypertension and normals.

Methods: : Ninety eyes from 90 patients were selected in which: 30 were recently diagnosed with glaucoma before starting any ocular hypotensive medications, 30 had elevated intraocular pressure (IOP>mention the number) without any evidence of glaucoma, and 30 were included in the control group with normal IOP and without any evidence of glaucoma. They underwent Goldmann applantion tonometry, dymanic contour tonometry (Pascal), blood pressure (BP), pachymetry, Humphrey visual field (except the control group), and routine ophthalmologic examination. The OPP was calculated by the difference between mean arterial blood pressure and IOP. The OPA was measured by the Pascal tonometer.

Results: : Mean OPA in the glaucoma group was 3.4 ± 1.2 mmHg, ocular hypertensive 3.5 ± 1.2 mmHg, and normals 2.6 ± 0.9 mmHg. Mean OPP was 46.3 ± 7.9 mmHg in the glaucoma group, 46.3 ± 7.9 mmHg in the ocular hypertensive, and 50.2 ± 7.0 mmHg in the normals. Neither groups showed significant correlation (p-value > 0.05) between OPP and OPA. Pearson coefficient test was used for corelation between glaucoma and ocular hypertensive groups , while Spearman’s rank coefficient correlation was used to test for the normal group.

Conclusions: : OPP and OPA values do not correlate with each other in individuals with glaucoma, ocular hypertensive and normals.

Keywords: optic flow • blood supply • outflow: trabecular meshwork 

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