Purchase this article with an account.
Alexandros Deligiannidis, Jose Lorenzo Carrero; Evaluation Of Macular Ischemia In Diabetic Macular Edema. Invest. Ophthalmol. Vis. Sci. 2012;53(14):380.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To evaluate the relationship between the macular ischemia and the visual acuity in patients with diabetic macular edema.
Sixty-two eyes from 37 patients diagnosed of diabetic macular edema and with transparent media were included in the study. A comprehensive ophthalmologic examination was carried out. All patients underwent a digital high resolution fluorescein angiography with a non-flash blue laser (488nm) confocal ophthalmoscope (SPECTRALIS HRA2+OCT). Consecutively, a Spectral-Domain OCT with active eye tracking was performed. The OCT data obtained included foveal thickness, macular volume and the disruption of the foveal photoreceptor layer. The ischemia was quantified with a computer-assisted image analysis software. Data from one eye of each patient were assessed with Pearson and Spearman correlation analysis.
Visual acuity was correlated significantly only with the disruption of the foveal photoreceptor layer (P = ,022, r= - 0,397). The macular ischemia was strongly correlated with the disruption of the foveal photoreceptor layer (P = ,013, r = 0,428), but not with the macular volume, nor with the foveal thickness.
The macular ischemia was positively correlated with the disruption of the foveal photoreceptor layer, independently of the macular volume or the foveal thickness.
This PDF is available to Subscribers Only