March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Intravitreal Bevacizumab Injections can Release Vitreomacular Adhesions in Eyes with Persistent Diabetic Macular Edema and Vitreomacular Adhesions
Author Affiliations & Notes
  • Ramzi M. Al Judaibi
    Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia
  • Hanan Al Shamsi
    Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia
  • Nicola G. Ghazi
    Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia
  • Footnotes
    Commercial Relationships  Ramzi M. Al Judaibi, None; Hanan Al Shamsi, None; Nicola G. Ghazi, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 416. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Ramzi M. Al Judaibi, Hanan Al Shamsi, Nicola G. Ghazi; Intravitreal Bevacizumab Injections can Release Vitreomacular Adhesions in Eyes with Persistent Diabetic Macular Edema and Vitreomacular Adhesions. Invest. Ophthalmol. Vis. Sci. 2012;53(14):416.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract 
 
Purpose:
 

to report cases of persistent diabetic macular edema (DME) with vitreomacular adhesions (VMA) that responded to intravitreal bevacizumab (IVB) injection with separation of the VMA and complete or significant resolution of DME

 
Methods:
 

Three eyes of three patients were diagnosed with persistent DME and VMA following focal laser therapy based on typical clinical, angiographic, and spectral-domain optical coherence tomography (SD-OCT, Spectralis, Heidelberg, Germany) findings. A trial of IVB was attempted prior to proceeding with pars plana vitrectomy (PPV) to address the VMA.

 
Results:
 

All eyes disclosed cystoid macular edema with perifoveal vitreous separation and focal adhesion of the posterior hyaloid at the fovea on SD-OCT. Following one to three injections of IVB, SD-OCT showed complete separation of the VMA in all eyes with complete or significant resolution of the intraretinal fluid.

 
Conclusions:
 

Our findings suggest that a trial of intravitreal therapy, such as IVB, should be attempted in eyes with persistent DME and focal VMA before proceeding to PPV. The mechanical effect of the intravitreal injections may lead to separation of the VMA. This, together with the pharmacological effect of the injected agent, may lead to resolution of the DME as seen in the cases reported herein.

 
Keywords: retinal adhesion • diabetic retinopathy • edema 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×