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Alain M. Bron, Anna Francoz, Frederic Nicot, Serge Aho, Niyazi Acar, Lionel Bretillon, Catherine P. Garcher; Is Spectral Domain Optical Coherence Tomography Useful In Improving The Contour Line With The Heidelberg Retina Tomograph?. Invest. Ophthalmol. Vis. Sci. 2012;53(14):656.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the measurements of the optic disc in glaucoma patients and glaucoma suspects with spectral domain optical coherence tomography (SD-OCT) and confocal scanning laser ophthalmoscopy (HRT) before and after adjustment of the contour line with the help of the OCT.
In 109 consecutive patients (109 eyes), optic disc parameters were compared prospectively between the 2 devices before and after adjustment of the optic disc area (ODA) on the HRT3 with ODA obtained with the Cirrus SD-OCT as a reference. Intraclass correlation coefficients (ICC) and the 95% limits of agreement (LoA) with Bland-Altman plots were used to compare the agreement of the pre and post-adjustment measurements with the OCT and the HRT.
The ICC for the optic disc area (ODA) was better after adjustment of the contour line on the HRT3 with the help of ODA obtained with the OCT, 0.785 and 0.985, respectively. However the ICC for the rim area (RA) was still moderate after the adjustment, 0.543 and 0.627 respectively. Other parameters C/D ratio, cup area and cup volume were almost unchanged. The 95% limits of agreement (LoA) with Bland-Altman analysis were narrowed after the adjustment of the ODA, from -0.52 to + 0.71 mm2 to -0.12 to + 0.15 mm2. However the LoA remained wide for the RA even after correction of the contour line on the HRT with the help of the OCT, -0.32 to + 0.74 mm2 vs -0.23 to +0.61 mm2.
SD-OCT is an additional valuable tool in improving the placement of the contour line on the HRT. However the parameters of the optic disc measured by the 2 methods are not interchangeable.
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