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Chiara M. Eandi, Camilla G. Alovisi, Alessandro Reineri, Federico M. Grignolo; Simple Method Of Analysis Of Drusen Volume. Invest. Ophthalmol. Vis. Sci. 2011;52(14):154.
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To evaluate drusen volume with spectral domain OCT (SD-OCT) in patients with dry AMD.
We analyzed 30 eyes with drusen in dry AMD. Infrared (IR) and fundus autofluorescence (FAF) images (HRA, Heidelberg Engeneering, Heidelberg, Germany) were recorded as well as the en- face SD-OCT scans using the drusen volume modality (RTVue, Optovue) . Visual acuity measurement with ETDRS chart and fundus examination were also performed.
Drusen were visible with IR images in every patient, while FAF better revealed the presence of drusen in patients with medium or soft drusen. IR images and en-face SD-OCT scans can detect small drusen with more precision and details than FAF. The en-face SD-OCT images showed the presence of the drusen in all patients and we were able to record and measure their volume thanks to the drusen volume modality which gives more detailed informations about the progression of dry AMD than IR images and FAF .
The SD-OCT with the drusen volume modality is a non-invasive imaging technique that might help in the monitoring the progression of dry AMD.
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