April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
The Effect Of Cataract Grade And Location On Quality Of Ocular Imaging Scans
Author Affiliations & Notes
  • Jonathan Erickson
    Glaucoma,
    Bascom Palmer Eye Institute, Palm Beach Gardens, Florida
  • Maria Cecilia Reyes
    Glaucoma,
    Bascom Palmer Eye Institute, Palm Beach Gardens, Florida
  • Namita Bhardwaj
    Glaucoma,
    Bascom Palmer Eye Institute, Palm Beach Gardens, Florida
  • Wei Shi
    Ophthalmology, Biostatistics, University of Miami, Miami, Florida
  • Mitra Sehi
    Glaucoma,
    Bascom Palmer Eye Institute, Palm Beach Gardens, Florida
  • David S. Greenfield
    Ophthalmology,
    Bascom Palmer Eye Institute, Palm Beach Gardens, Florida
  • Footnotes
    Commercial Relationships  Jonathan Erickson, None; Maria Cecilia Reyes, None; Namita Bhardwaj, None; Wei Shi, None; Mitra Sehi, None; David S. Greenfield, Carl Zeiss Meditech (C, R), Heidelberg Engineering (R), Optovue Inc (C, R)
  • Footnotes
    Support  RO1-EY013516, Bethesda, Maryland and an unrestricted grant from Research to Prevent Blindness P30-EY14801, New York, New York.
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 168. doi:
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      Jonathan Erickson, Maria Cecilia Reyes, Namita Bhardwaj, Wei Shi, Mitra Sehi, David S. Greenfield; The Effect Of Cataract Grade And Location On Quality Of Ocular Imaging Scans. Invest. Ophthalmol. Vis. Sci. 2011;52(14):168.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine the effect of cataract grade and location on quality of imaging scans obtained using confocal scanning laser ophthalmoscopy (CSLO), scanning laser polarimetry (SLPVCC and ECC), time-domain OCT (TDOCT), and fourier-domain OCT (FDOCT).

Methods: : Phakic eyes of normal, glaucoma suspect, and glaucomatous patients meeting eligibility criteria were prospectively studied. One eye per subject was enrolled. Subjects underwent ophthalmologic examination and cataract grading was performed according to the Lens Opacities Classification System (LOCS III). Ocular imaging scans were performed at a single session by the same operators. Image quality measures consisted of pixel standard deviation (CSLO), typical scan score and Q score (SLPVCC and ECC), signal strength (TDOCT), and SSI (FDOCT). Mean quality measures were calculated from two imaging exams performed at the same session. Pearson correlation coefficients were calculated to examine the association between nuclear, cortical, and posterior subcapsular scores and imaging quality measures.

Results: : Thirty-five eyes of 35 patients (3 normal, 24 glaucoma suspect, 8 glaucoma) were enrolled. The mean age was 65.3 + 8.7 years. Mean logMAR visual acuity was -0.0163 + 0.069 (20/20). Average LOCS III grade for each cataract location were; nuclear 2.44, cortical 0.78, and posterior subcapsular 0.39. There was a significant correlation between higher nuclear opalescence and color scores and greater CSLO standard deviation values (r =0.62, p <0.001). Q score, TSS, signal strength, and SSI did not correlate with nuclear, cortical, or posterior subcapsular grades.

Conclusions: : Image quality scores using SLPVCC and ECC, TDOCT, and FDOCT are unaffected by early cataract. Nuclear cataract adversely affects CSLO standard deviation.

Keywords: imaging/image analysis: clinical • cataract • nerve fiber layer 
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