Purchase this article with an account.
Thiago L. Costa, Sr., Mirella T. Barboni, Mirella Gualtieri, Ana L. Moura, Luiz Carlos L. Silveira, Dora F. Ventura; Effects Of Occupational Exposure To A Solvent Mixture On Chromatic And Achromatic Vision Of Gas Station Workers. Invest. Ophthalmol. Vis. Sci. 2011;52(14):268.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To evaluate the visual outcome of chronic occupational exposure to a mixture of organic solvents in a group of gas station workers.
We tested 25 workers (20 male; age=36,4±8,9 years) and 25 controls with no history of chronic exposure to solvents (10 male; age=33,8±8,8 years). All participants had normal visual acuity and no ophthalmological complaints. Urinary concentrations of toluene (M=0,3±0,16g/g of creatinine) and xylene metabolites (M=0,1 g/g of creatinine), were within safe limits. Time of exposure was (M=9,6±6,2 years), used as indicators of the exposure. Color vision was evaluated with the Lanthony D15d and Cambridge Colour Test (CCT). Visual field were assessed with automatic white-on-white 24-2 perimetry (Humphrey II-750i). mfVEP were assessed in three workers (Veris Science 5.2.4). Contrast sensitivity (Metropsis software) was measured with sine wave gratings of 0,2; 0,5; 1,0; 2,0; 5,0; 10,0 and 20,0 cpd. The groups were compared using the Mann-Whitney U test.
In the CCT, there were significant differences for the area of the ellipse, elipticity and thresholds for the protan, deutan and tritan confusion axes (p<0,05). Significant differences between the groups were also found for the D15d (p<0,01) and for the automated perimetry results for the 9o, 15o and 21o eccentricity rings (p<0,05), MD and PSD (p<0,05). Each subject from the workers group showed at least 30 sectors of the visual field with significantly reduced amplitude (p<0,05) in the mfVEP when compared to normative data, while control group subjects had a maximum of 16 sectors of reduced amplitude. Significant correlation was found between time of work and deutan axis thresholds (π=0,59; p<0,05), indexes of the Lanthony D15d (π=0,52; p<0,05), perimetry results in the Fovea (π=-051; p<0,05) and at 3, 9 and 15 degrees of eccentricity (π=-0,46; p<0,05).
Losses in visual function were found for chronic exposure to organic solvents even at exposures within occupational safety limits. The visual changes found were extensive and diffuse.
This PDF is available to Subscribers Only