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Anzhelika Berezovskaya, Victor Gunter, Igor Zapuskalov; Medico-Technological System of Keratoprosthetics. Invest. Ophthalmol. Vis. Sci. 2011;52(14):334.
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To develop effective and safe method of keratoprosthesis for patients with advances corneal leukoma.
Keratoprosthesis consists of two parts. Optic lens is made of polymethylmethacrylate. Haptic part is made of porous titanium nickelide (TN). Use of the TN alloy allows for integration of the optics and haptics by simple mechanical overlaying. It also allows for one-phase full-thickness prosthetic surgery. During the 7-year period, 11 patients with advanced corneal leukoma from various pathology of the anterior segment of the eye were implanted with this keratoprosthesis. Main indication for this type of surgery was considered stage IV-V leukoma with preserved retinal and optic nerve functions detected on full-field and flash electroretinography (ERG) and evaluation of phosphenes. All patients had visual acuity (VA) of light perception.
Increase in VA to 0.01-0.4 was achieved in 8 patients. VA in the rest 3 patients remained at light perception due to their persistent post-traumatic glaucoma and consequent glaucomatous optic nerve atrophy.
The suggested system for keratoprosthetics has demonstrated that the elastic porous metal did not cause major disturbances to the anatomy and physiology of the eye structures such as corneal disintegration, rejection reaction or formation of retinoprosthetic membrane, complications which are common with other types of keratoprostheses.
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