April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Identification Of Electrodes In Visual Prosthesis Using Suprachoroidal- Transretinal Stimulation
Author Affiliations & Notes
  • Takao Endo
    Department of Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Takashi Fujikado
    Department of Applied Visual Science,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Motohiro Kamei
    Department of Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Hirokazu Sakaguchi
    Department of Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Hiroyuki Kanda
    Department of Applied Visual Science,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Takeshi Morimoto
    Department of Applied Visual Science,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Haruhiko Kishima
    Department of Neurosurgery,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Kunihiko Konoma
    Nidek Co., Gamagori, Japan
  • Motoki Ozawa
    Nidek Co., Gamagori, Japan
  • Kohji Nishida
    Department of Ophthalmology,
    Osaka University Graduate School of Medicine, Suita, Japan
  • Footnotes
    Commercial Relationships  Takao Endo, None; Takashi Fujikado, Nidek Co. (F); Motohiro Kamei, None; Hirokazu Sakaguchi, None; Hiroyuki Kanda, Nidek Co. (F); Takeshi Morimoto, None; Haruhiko Kishima, None; Kunihiko Konoma, Nidek Co. (E); Motoki Ozawa, Nidek Co. (E); Kohji Nishida, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 443. doi:
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      Takao Endo, Takashi Fujikado, Motohiro Kamei, Hirokazu Sakaguchi, Hiroyuki Kanda, Takeshi Morimoto, Haruhiko Kishima, Kunihiko Konoma, Motoki Ozawa, Kohji Nishida; Identification Of Electrodes In Visual Prosthesis Using Suprachoroidal- Transretinal Stimulation. Invest. Ophthalmol. Vis. Sci. 2011;52(14):443.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Recently, various types of visual prosthesis have been developed. The position of electrode array can be easily identified in cases with epi- or sub- retinal prosthesis because electrodes are visible under the funduscope. However, in our originally developed visual prosthesis using suprachoroidal- transretinal stimulation (STS), it is difficult to identify the electrode array because it is buried in the sclera. In this study, we tried to identify electrode array with OCT images and investigated the relationship between the position of electrode and that of phosphene which was elicited by electrical stimulation.

Methods: : The patient was a 67 year-old woman with advanced retinitis pigmentosa and had a vision of light perception (OU). We created a scleral pocket around the insertion of the inferior oblique muscle toward the optic nerve in her left eye (from infero-temporal side) and inserted a 7×7 electrode array in the pocket. The internal device was fixed under the skin of the left temporal area. One week after the surgery, we recorded the position of phosphene in response to the electrode stimulation and examined the position of the electrode array with OCT (SpectralisTM).

Results: : When we stimulated the tip electrode of the electrodes array, phosphene was recorded at (only) 2° nasal and 2° upper side from the center of visual field. In OCT slices at or lower area of the fovea, the elevation of choroid, which was presumed position of the electrode array, was observed at temporal side.

Conclusions: : The OCT images suggested that the head of the electrode array was positioned just lower temporal side of the fovea. This agrees with the position of scleral pocket created during surgery and with the position of phosphene recorded after surgery. These results suggest that we can insert electrode array by STS method near the fovea as epi- or sub-retinal prosthesis.

Keywords: accessory optic system/pretectum • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retina 
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