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Hyun Jun Park, Jae Ho Jung, Jong Hun Shin, Ik Soo Byon, Ji Eun Lee, Boo Sup Oum; Changes of Macular Thickness after Panretinal Photocoagulation related to Fluorescein Leakage in Diabetic Retinopathy without Macular Edema. Invest. Ophthalmol. Vis. Sci. 2011;52(14):572.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate changes of macular thickness after panretinal photocoagulation(PRP) related to degree of fluorescein leakage in diabetic retinopathy without macular edema.
Eyes having diabetic retinopathy without macular edema were divided into three groups according to degree of fluorescein leakage at 9 subfields in 6mm area of the macula. Macular thickness at 9 subfields were measured using OCT before and after PRP. Cases with history of focal laser or intravitreal injection for macular edema were excluded.
We retrospectively studied 64 eyes from 50 patients with diabetic retinopathy. The changes of macular thickness at central 1mm diameter were significantly different among 3 groups according to fluorescein leakage at 1mm diameter (p=0.004, by oneway ANOVA). The changes of macular thickness at 3mm and 6mm diameter were also significantly different among 3 groups according to fluorescein leakage at 1mm diameter (p=0.003, 0.004 by oneway ANOVA). The changes of visual acuity before and after PRP were not different among 3 groups.
The degree of fluorescein leakage at fovea in diabetic retinopathy without macular edema was predictive for development of macular edema after PRP.
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