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Mayra S. Mendez, Rafael A. Bueno-Garcia; Correlation Features Between Fluorescein Angiogram And Optical Coherence Tomography In Clinically Significant Diabetic Macular Edema In Mexican Patients. Invest. Ophthalmol. Vis. Sci. 2011;52(14):586.
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To assess the correlationship between the features of optical coherence tomography (OCT) and fluorescein angiography in clinically significant diabetic macular edema. (CSDME)
This study involved 11 eyes (8 patients) with significant diabetic macular edema. The fluorescein angiography features were categorized into focal leakage type, diffuse leakage type, and diffuse cystoid leakage type. The OCT features were categorizedinto four types: type 1 (thickening with homogenous optical reflectivity), type 2 (thickening with markedly decreased optical reflectivity in the outer retinal layer), type 3A (foveolar detachment without traction) and type 3B (foveolar detachment with apparent vitreofoveal traction). The correlation between fluorescein angiography types and OCT types were analyzed, and their associations with visual acuity and central foveal thickness. Diabetic retinopathy stages were also evaluated.
The age of patients ranged between 47 and 60 years. The minimum duration of the development of diabetes was 9 years, maximum 20 years. The 36.6% of patients met RDFC with activity, 27.7% with no history of photocoagulation RDP, 18.8% with moderate RDNP and 18.8% with severe RDNP. The prevalence of OCT type 1 was higher in the focal leakage type (45.5%) and in the diffuse leakage type (27.27%). The prevalence of OCT type 2 with diffuse leakage was 18.8% and focal leakage was 10%.
The most frequent type in fluorescein angiography was the diffuse, next on the list the focal leakage type, while OCT the most frecuent type was number 1, followed by type 2. Focal edema in the fluorescein angiography is associated with top thickness in OCT and better visual acuity.
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