April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
A Combined Low Energy, Short Pulsed 577 nm Mild Macular Grid Photocoagulation with 577 nm-Micropulsed Central Laser Stimulation for Diabetic Macular Edema with Foveal Leakage (The Sandwich Grid)
Author Affiliations & Notes
  • Renato Peroni
    Retina Department, Centro Brasileiro de Especialidades Oftalmológicas (CBEO), Araraquara, SP, Brazil
  • Jose A. Cardillo
    Hospital de Olhos de Araraquara, Araraquara, SP, Brazil
    Federal University of Sao Paulo, UNIFESP, Sao Paulo, SP, Brazil
  • Alessandro J. Dare
    Retina Department, Centro Brasileiro de Especialidades Oftalmológicas (CBEO), Araraquara, SP, Brazil
  • Joao Guilherme Aguirre
    Retina Department, Centro Brasileiro de Especialidades Oftalmológicas (CBEO), Araraquara, SP, Brazil
  • Daniel Lavinsky
    Federal University of Sao Paulo, UNIFESP, Sao Paulo, SP, Brazil
  • Michel E. Farah
    Federal University of Sao Paulo, UNIFESP, Sao Paulo, SP, Brazil
  • Rubens Belfort, Jr.
    Federal University of Sao Paulo, UNIFESP, Sao Paulo, SP, Brazil
  • Footnotes
    Commercial Relationships  Renato Peroni, None; Jose A. Cardillo, None; Alessandro J. Dare, None; Joao Guilherme Aguirre, None; Daniel Lavinsky, None; Michel E. Farah, None; Rubens Belfort, Jr., None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 590. doi:https://doi.org/
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      Renato Peroni, Jose A. Cardillo, Alessandro J. Dare, Joao Guilherme Aguirre, Daniel Lavinsky, Michel E. Farah, Rubens Belfort, Jr.; A Combined Low Energy, Short Pulsed 577 nm Mild Macular Grid Photocoagulation with 577 nm-Micropulsed Central Laser Stimulation for Diabetic Macular Edema with Foveal Leakage (The Sandwich Grid). Invest. Ophthalmol. Vis. Sci. 2011;52(14):590. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To determine the anatomical and functional outcome of combined barely visible 577nm photocoagulation lesions placed throughout the macula and microaneurysms area with a 577 nm-micropulsed central photo stimulation in patients with diabetic macular edema (DME) with foveal leakage.

Methods: : Twenty-eight eyes of 25 patients with DME were treated using a yellow diode laser (577 nm) clinically adjusted to show barely visible photocoagulation lesions at 10 ms exposure time. The mean retinal sensitivity within the central 10 degrees measured with a fundus-related microperimeter, MP1, ETDRS-best corrected visual acuity (BCVA), optical coherence tomography-determined central macular thickness (CMT), and fluorecein angiography (FA) were performed before, 1, 3 and 6 months after a single treatment.

Results: : Central macular thickness decreased by an average of 201µm. At 6 months main change in visual acuity was 3 letters better. Mean macular sensitivity improved (P<0.005) at 3 and 6 months. Laser lesions were not clinically observed, but detected on FA examination. The foveal area no signs of treatment could be observed by any means.

Conclusions: : In the effort to minimize the side effects while maintaining the efficacy, combination of mild macular grid and foveal micropulse may characterize a more selective alternative to progress macular photocoagulation for DME with central foveal leakage.

Keywords: diabetic retinopathy • laser • retina 
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