March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
3-D Image Guided Retinal Surgery Using Real-Time High-Speed Fourier-Domain Optical Coherence Tomography
Author Affiliations & Notes
  • Peter L. Gehlbach
    Ophthalmology, Johns Hopkins Wilmer Eye Inst, Baltimore, Maryland
  • Yong Huang
    Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland
  • Jin U. Kang
    Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland
  • Footnotes
    Commercial Relationships  Peter L. Gehlbach, None; Yong Huang, None; Jin U. Kang, None
  • Footnotes
    Support  RO1 EY021540-01A1
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 807. doi:
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    • Get Citation

      Peter L. Gehlbach, Yong Huang, Jin U. Kang; 3-D Image Guided Retinal Surgery Using Real-Time High-Speed Fourier-Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2012;53(14):807.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To demonstrate an innovative microsurgical approach using a real-time, 3-dimensional optical coherence tomography imaging system to perform 3-D image guided basic microsurgical procedures.

Methods: : A novel microsurgical imaging system based on a Fourier-Domain OCT (FD-OCT) integrated with a CPU-GPU heterogeneous computing architecture capable of OCT image processing and displaying at the maximum processing speed of approximately 252,000 A-scans/second based on NUFFT and 10 volumes/second for complex conjugate free FD-OCT was used to provide real-time 3-D video imaging of the surgical site and tool tips while basic surgical maneuvers were performed in ex vivo bovine eyes. The imaged site size was 3mm×3mm×3mm (Width × Length × Depth) sampled by 160×80x1024 pixels and was rendered to the surgeon with top, front-side and back-side views by a ray casting method. Two basic maneuvers were repeatedly performed and successfully confirmed: retinal vessel isolation with micro-pick confirmed by retinal vessel isolation with suture; subretinal cannulation with delivery of fluid confirmed by subretinal cannulation with delivery of air.

Results: : Using the 3-D surgical OCT viewing environment as the primary source of visualization, we were able to successfully perform and repeat the prototypical microsurgical maneuvers described using the retina as a model system. For each procedure there is a learning curve related to working predominantly in a 3-D OCT image environment. The data consists of video frames of all key steps. In all cases the OCT viewing environment was referenced to direct photography and or direct visualization.

Conclusions: : The present prototype real-time, 3-dimensional optical coherence tomography imaging system allows for the performance of basic microsurgical maneuvers using the OCT viewing environment as the primary source of visual information.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • motion-3D • vitreoretinal surgery 
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