March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
High Resolution Optical Coherence Tomography Retinal and Choroidal Findings in Ocular Toxoplasmosis
Author Affiliations & Notes
  • Michaella Goldstein
    Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel
  • Zohar Habot-Wilner
    Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel
  • Anat Loewenstein
    Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel
  • Dafna Goldenberg
    Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel
  • Footnotes
    Commercial Relationships  Michaella Goldstein, None; Zohar Habot-Wilner, None; Anat Loewenstein, None; Dafna Goldenberg, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 819. doi:
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      Michaella Goldstein, Zohar Habot-Wilner, Anat Loewenstein, Dafna Goldenberg; High Resolution Optical Coherence Tomography Retinal and Choroidal Findings in Ocular Toxoplasmosis. Invest. Ophthalmol. Vis. Sci. 2012;53(14):819.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To demonstrate the different retinal and choroidal morphological characteristics on SD Optical Coherence Tomography (OCT) in ocular toxoplasmosis.

Methods: : Case series of patients presented with ocular toxoplasmosis from August 2009 were included in the study. All patients underwent a detailed ophthalmic examination, fundus color photography and Spectralis SD-OCT imaging at presentation and during follow-up. OCT scans were directed to the pathological retinal and choroidal areas that were demonstrated in the clinical examination.

Results: : Sixteen eyes (13 patients) were included. Eleven active lesions were demonstrated in 9 eyes (8 patients) and 25 chorioretinal scars were demonstrated in 12 eyes (10 patients). The active lesion demonstrated retinal thickening, disruption and hyper-reflectivity of the retinal layers. During follow-up the retina became thinner and a scar formation was noted. Hyper-reflective deposits were noted on the posterior hyaloid, within the vitreo-retinal interface and in the inner retina layres. Those deposits fade with time. Vitritis could be demonstrated as multiple hyper-reflective dots in the vitreous cavity during the active phase, which resolved during follow-up. Choroidal findings included significant thickening returning to normal thickness when scars were formed.OCT findings of the chorioretinal scars demonstrated sharply demarcated borders, thinning of neurosensory retina, ELM & IS/OS junction interruption, disorganization of the retinal layers and RPE changes. The choriocapillaries demonstrated a specific pattern with a significant hypereflectivity. In addition, the posterior hyaloid was thickened and partially detached over the toxoplasma scar. The OCT retinal and choroidal features remained unchanged during the follow up.

Conclusions: : SD-OCT is a useful tool in the diagnosis and follow-up of patients with ocular toxoplasmosis and provides a better understanding of the pathogenesis of the disease.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • chorioretinitis • imaging/image analysis: clinical 

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