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Akshay S. Thomas, Raul Seballos, Richard Lang, Rishi P. Singh; Does Spectral Domain OCT Provide Any Additional Useful Information to Non-Mydriatic Fundus Photography in the Screening of Asymptomatic Patients?. Invest. Ophthalmol. Vis. Sci. 2012;53(14):835. doi: https://doi.org/.
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In this single center, prospective study, we examine whether Spectral Domain OCT can add any additional useful information to non-mydriatic single-field fundus photography in the evaluation of the retina and vitreoretinal interface of asymptomatic patients. The primary outcome from this study is to identify if Spectral Domain OCT can serve as an adjunct to non-mydriatic fundus photography as a screening tool in the ambulatory setting.
Spectral Domain OCT imaging of both eyes was obtained from 568 consecutive patients as part of an executive health clinic. Images were obtained with sections through the macula as well as the optic disk. Corresponding non-mydriatic single-field fundus photographs including the macula and optic disk were obtained for these patients. Review of the fundus photography was done by a single observer and OCT review was done by a different observer. Each observer was blinded to the results of the imaging modality that they were not reviewing. Findings on OCT were tabulated and compared to those on fundus photography. Additional diagnostic findings on Spectral Domain OCT were noted and patients were contacted for follow-up if clinically indicated.
OCT scans were adequate in both eyes of 534 (94%) patients. OCT findings were normal in both eyes of 196 (36.7%) patients. VMT was seen in at least one eye of 287 (53.7%) patients. PVD was seen in 33 (6.18%) patients. ERM was seen in 20 (3.75%) patients. An abnormal foveal contour was found in 17 (3.2%) patients. Drusen was seen in 14 (2.62%) patients. Lamellar holes and pseudoholes were each seen in 2 (0.38%) patients. Cystoid macular edema and sub-RPE fluid were each seen in 1 (0.19%) patient. The mean central retinal thickness was 253 µm (SD: 28.9 µm).
Though SD-OCT provides an abundance of information, its use as a screening tool in asymptomatic patients is limited by a low incidence of findings requiring an ophthalmic intervention.
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