Abstract
Purpose: :
To investigate the time-period characteristics associated with morphologic changes incentral serous chorioretinopathy (CSC) using cube volumescans acquired by spectral-domainoptical coherence tomography(SD-OCT).
Methods: :
Patients underwent visual acuity measurement, fundus examination, fluorescein angiography (FA), indocyanin green angiography (IA), and SD-OCT cube volume scans. Patients were classified into three groups according to the onset of subjective symptomsof 6 weeks and 6 months. SD-OCT findings among the three groups were evaluated and compared.
Results: :
A total of 45 eyes from three groups of 15 patients each were included in the study.Shallow retinal detachment was observed significantly more in eyes withlate chronic CSC than in eyes with acute and early chronic CSC (P=0.001, 0.021,respectively). Shallow irregular pigment epithelial detachment (PED) was observed significantly more in eyes with early chronic CSC than in eyes with acute and late chronic CSC (P=0.035, 0.035, respectively). Flat PED was observed significantly more in eyes with late chronic CSC than in eyes with acute and early chronic CSC (P=0.035, 0.035, respectively). Posterior granulations or subretinal precipitations were observed significantly more in eyes with early chronic and late chronic CSC than in eyes with acute CSC (P=0.021, 0.003, respectively). Fibrinous exudates were observed significantly more in eyes with early chronic CSC than in eyes with acute CSC (P=0.017).
Conclusions: :
Detailed investigation of the RPE and outer retina using SD-OCT could help estimate the duration of CSC.
Keywords: imaging/image analysis: clinical • retina • retinal pigment epithelium