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Yutaka Imamura, Kouhei Hashizume, Takamitsu Fujiwara, Shigeki Machida, Masahiro Ishida, Daijiro Kurosaka; Choroidal Thickness In Eyes With Recurrent Vogt-Koyanagi-Harada Disease. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1158.
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To investigate the change of choroidal thickness in eyes showing recurrent inflammation during the follow-up of Vogt-Koyanagi-Harada disease (VKH) after high-dose steroid therapy.
Choroidal thicknesses in eyes with VKH were reviewed during the follow-up after high-dose steroid therapy. Choroidal thickness was measured using enhanced depth imaging optical coherence tomography. Recurrence of inflammation was defined as a condition which needed more dose of oral steroid than that used previously.
Among 17 patients with VKH (mean age: 52 years), 8 patients showed recurrent inflammation during the follow-up. The mean choroidal thickness in eyes with recurrent inflammation was 421±125 μm, which was significantly larger than that measured at the previous examination (297±93 μm, Student t test, P<0.01).
Choroid becomes thick in eyes with relapsing VKH. Thickening of choroid may be a hallmark of recurrence of inflammation during the follow-up of VKH after high-dose steroid therapy.
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