March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Choroidal Thickness In Eyes With Recurrent Vogt-Koyanagi-Harada Disease
Author Affiliations & Notes
  • Yutaka Imamura
    Ophthalmology, Teikyo University School of Medicine, Kawasaki, Japan
  • Kouhei Hashizume
    Ophthalmology, Iwate Medical University School of Medicine, Morioka, Japan
  • Takamitsu Fujiwara
    Ophthalmology, Iwate Medical University School of Medicine, Morioka, Japan
  • Shigeki Machida
    Ophthalmology, Iwate Medical University School of Medicine, Morioka, Japan
  • Masahiro Ishida
    Ophthalmology, Teikyo University School of Medicine, Kawasaki, Japan
  • Daijiro Kurosaka
    Ophthalmology, Iwate Medical University School of Medicine, Morioka, Japan
  • Footnotes
    Commercial Relationships  Yutaka Imamura, None; Kouhei Hashizume, None; Takamitsu Fujiwara, None; Shigeki Machida, None; Masahiro Ishida, None; Daijiro Kurosaka, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 1158. doi:https://doi.org/
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    • Get Citation

      Yutaka Imamura, Kouhei Hashizume, Takamitsu Fujiwara, Shigeki Machida, Masahiro Ishida, Daijiro Kurosaka; Choroidal Thickness In Eyes With Recurrent Vogt-Koyanagi-Harada Disease. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1158. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To investigate the change of choroidal thickness in eyes showing recurrent inflammation during the follow-up of Vogt-Koyanagi-Harada disease (VKH) after high-dose steroid therapy.

 
Methods:
 

Choroidal thicknesses in eyes with VKH were reviewed during the follow-up after high-dose steroid therapy. Choroidal thickness was measured using enhanced depth imaging optical coherence tomography. Recurrence of inflammation was defined as a condition which needed more dose of oral steroid than that used previously.

 
Results:
 

Among 17 patients with VKH (mean age: 52 years), 8 patients showed recurrent inflammation during the follow-up. The mean choroidal thickness in eyes with recurrent inflammation was 421±125 μm, which was significantly larger than that measured at the previous examination (297±93 μm, Student t test, P<0.01).

 
Conclusions:
 

Choroid becomes thick in eyes with relapsing VKH. Thickening of choroid may be a hallmark of recurrence of inflammation during the follow-up of VKH after high-dose steroid therapy.  

 
Keywords: imaging/image analysis: clinical • choroid • autoimmune disease 
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