Abstract
Purpose: :
To evaluate retinal blood flow using the RFI to monitor PRP response.
Methods: :
The RFI captures blood flow sequences that mirror clinical changes. RFI imaging was performed pre and post PRP.
Results: :
Mean venous velocities before and after PRP treatment were 2.82 +/- 0.61 mm/sec and 2.62 +/- 0.37 mm/sec after PRP, suggesting a significant decrease of at least 14.04% (p =0.03). Mean arterial velocities before PRP treatment were 4.48 +/- 1.42 mm/sec and 4.46 +/- 1.57 mm/sec after PRP which was not significant.
Conclusions: :
The RFI may prove useful in the clinical management of diabetic patients undergoing laser therapy. Reduced venous velocity could serve as a non-invasive surrogate endpoint of laser effectiveness for suppression of PDR activity.
Keywords: diabetic retinopathy • retinal neovascularization • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)