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Vandhana Surendranath, Ashwin C. Mallipatna, Rajani Battu, Nafisa Saifudeen, Supriya Dabir; Image Retinoblastoma Tumors Using the Bioptigen Hand-Held Spectral Domain Ophthalmic Imaging System. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1165.
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The Bioptigen Hand-Held Spectral Domain Optical Coherence Tomography (hh-SDOCT) can acquire depth-resolved images of ocular tissue microstructure. A hand held imaging system is useful in imaging children supine
The hh-SDOCT was used to obtain serial scans of the retina of children with retinoblastoma. Large tumors were imaged with 12mm sections, while small early tumors, suspicious areas in the retina and seeds were imaged with 6 or 4mm sections in rectangular and radial frames
We imaged tumors in 23 patients. Tumors could be imaged up to a depth of 3mm. Response to focal therapy and reducing tumor size was documented. Small new lesions would arise from the inner nuclear layer with its density equivalent to it. Posterior pole lesions could be imaged with ease, and imaging lesions up to the equator were possible
The hh-SDOCT is a useful tool in monitoring children with retinoblastoma to detect small tumors and to potentially monitor for recurrence
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