Purpose:
To describe the clinical appearance and spectral domain optical coherence tomography (SD-OCT) findings of a series of patients with a novel vitreoretinal interface abnormality.
Methods:
We performed a retrospective, observational case study of 14 patients with hyperreflective vitreoretinal interface abnormalities in a scrolled configuration found on Heidelberg SD-OCT imaging. Demographic information, clinical characteristics and SD-OCT ultrastructural features were recorded.
Results:
Fourteen eyes of 14 patients were identified. The mean age was 60 years (range 28-77, median 65). Eight patients (57%) were male. Visual acuities were 20/40 or better in 7 eyes (50%), 20/50 to 20/200 in 6 eyes (43%), and worse than 20/200 in 1 eye (7%). Four patients (29%) were visually asymptomatic, while ten (71%) reported blurred vision or metamorphopsias. The vitreoretinal interface abnormalities were located above the fovea or parafoveal in eight (57%) and perifoveal in six eyes (43%). The mean SD-OCT central subfield thickness was 441 microns (range 249-1059, median 402). Three patients underwent pars plana vitrectomy and retinal membrane peeling. No intraoperative difficulties were encountered. Post-operatively, visual acuity and central subfield thickness improved, and the hyper-reflective material resolved. For the patients without surgical intervention and for whom follow-up SD-OCT was available, visual acuity improved or remained stable and the hyperreflective vitreoretinal interface abnormalities appeared unchanged.
Conclusions:
Focal contraction of the internal limiting membrane and epiretinal membrane can result in hyperreflective vitreoretinal interface abnormalities and may have a scrolled "egg-like" appearance on SD-OCT. Visual acuity is usually minimally affected in these conditions.
Keywords: retina • imaging/image analysis: clinical • vitreous