April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
the Repeatability and Agreement of Four Optical Coherence Tomography Systems
Author Affiliations & Notes
  • Lili Ge
    school of Opthalmology and Optometry, Wenzhou Medical College, Wenzhou, China
  • Aizhu Tao
    school of Opthalmology and Optometry, Wenzhou Medical College, Wenzhou, China
  • Meixiao Shen
    school of Opthalmology and Optometry, Wenzhou Medical College, Wenzhou, China
  • Jianhua Wang
    Ophthalmology, Bascom Palmer Eye Inst Lib, Miami, Florida
  • Fan Lu
    school of Opthalmology and Optometry, Wenzhou Medical College, Wenzhou, China
  • Footnotes
    Commercial Relationships  Lili Ge, None; Aizhu Tao, None; Meixiao Shen, None; Jianhua Wang, None; Fan Lu, None
  • Footnotes
    Support  Technology Development Supporting Program of the Eleventh Five-Year Plan, Beijing, China.
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 1019. doi:https://doi.org/
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    • Get Citation

      Lili Ge, Aizhu Tao, Meixiao Shen, Jianhua Wang, Fan Lu; the Repeatability and Agreement of Four Optical Coherence Tomography Systems. Invest. Ophthalmol. Vis. Sci. 2011;52(14):1019. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To investigate the repeatability and agreement of custom-built ultra-high resolution OCT (UHR-OCT), ultra-long scan depth OCT (UL-OCT), Visante OCT and Optovue OCT.

Methods: : The experiment included 2 parts. In part one, four RGP lenses with different thickness (0.11mm,0.12mm,0.15mm,0.17mm) were imaged by UHROCT, ULOCT, Visante and Optovue, respectively. In part two, eight eyes of 4 normal subjects were imaged and the central corneal thicknesses were obtained by the four OCT devices. Each subject was imaged in two inconsecutive days. For Visante and Optovue, the commercial software was used to obtain the central corneal thickness. For two custom-built OCT devices, custom-built automatic algorithm was used to obtain the thickness.

Results: : For four different RGP lenses, there was no difference between the thicknesses measured by UHROCT, ULOCT and the real values. There was no difference among UHROCT, ULOCT, Visante and Optovue in central corneal thickness (P > 0.05). The between-OCTs correlation coefficients are greater than 0.972. The mean differences of central corneal thickness between repeated visits measured by UHROCT, ULOCT, Optovue and Visante were 0.077 ± 2.256µm, -0.350 ± 2.804µm, 0.583 ± 2.394µm and -1.667 ± 2.325µm, respectively. There was no significant difference for central corneal thicknesses obtained in two inconsecutive days using the four OCT devices (P > 0.93).The correlation coefficients between visits were 0.990, 0.991, 0.997, 0.986 for UHROCT, ULOCT, Visante and Optovue, respectively.

Conclusions: : UHROCT and ULOCT appeared to have good repeatability and accuracy and have good agreement with Visante and Optovue.

Keywords: cornea: clinical science • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical 
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