March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
Quality of Vision after Wavefront-Guided or Wavefront-Optimized LASIK
Author Affiliations & Notes
  • Lingmin He
    Ophthalmology, Stanford University, Palo Alto, California
  • Edward E. Manche
    Ophthalmology, Stanford Univ Sch of Med, Palo Alto, California
  • Footnotes
    Commercial Relationships  Lingmin He, None; Edward E. Manche, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 1480. doi:
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    • Get Citation

      Lingmin He, Edward E. Manche; Quality of Vision after Wavefront-Guided or Wavefront-Optimized LASIK. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1480.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To compare the effect of wavefront-guided and wavefront-optimized LASIK on patient perceived quality of vision.

Methods: : 66 patients (132 eyes) were enrolled in this prospective study. One eye was randomized to undergo wavefront-guided LASIK treatment by the STAR S4 IR (VISX) system and the fellow eye to wavefront-optimized treatment by the Allegreto Wave system (Wavelight). Patients answered questionnaires on their visual symptoms and quality of vision preoperatively and at one, three, six, and twelve months after surgery. A paired t-test was used to compare symptom severity between the two treated eyes and also between pre- and post-operative symptoms.

Results: : Patients reported better vision at 12 months in the eye receiving wavefront-guided treatment (P = 0.042). No other postoperative symptoms were significantly different between the two groups. Eyes in both groups experienced significantly more glare, haze, and fluctuating vision until 12 months after treatment (P <0.001 - 0.039). An increase in halos persisted after 12 months. (P = 0.013- 0.041). Dry eye frequency and severity increased after 1 month (P <0.01-0.02) but was no longer significant after 3 months (P = 0.504 -0.850). No significant changes in grittiness and nighttime clarity of vision occurred.

Conclusions: : One year after surgery, patient self-reported visual symptoms were not significantly different in eyes receiving wavefront-guided or wavefront-optimized LASIK. However, patients reported significantly better overall vision in the eye which underwent wavefront-guided treatment.

Clinical Trial: : NCT01138189

Keywords: refractive surgery: optical quality • refractive surgery: comparative studies 

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