Abstract
Purpose: :
To compare the effect of wavefront-guided and wavefront-optimized LASIK by ALCON system on patients’ perceived quality of vision.
Methods: :
36 patients (72 eyes) were enrolled in this prospective study to undergo LASIK surgery using the Alcon Wavelight Allegretto Wave Eye-Q 400 Hz excimer laser system. One eye was randomized to undergo wavefront-guided LASIK and the fellow eye to wavefront-optimized LASIK. Patients answered questionnaires on their visual symptoms and quality of vision preoperatively and at one, three, and six months after surgery. A paired t-test was used to compare symptom severity between the two treated eyes and also between pre- and post-operative symptoms.
Results: :
Eyes in both groups experienced significantly more glare and haze frequency after 1 month (p=0.001- 0.036), but these symptoms were no longer significant at 6 months postoperatively (p=0.407-0.940). No significant changes in frequency of halos, clarity, double vision, or ghost images occurred in either group at both 3 months and 6 months post-operatively. Eyes in both groups experienced significantly improved vision at 3 and 6 months postoperatively (p <0.001 - 0.013). Of the 31 patients who self-evaluated their overall vision, 32.3% (n=10) reported better vision in the eye receiving wavefront-guided LASIK, 25.8% (n=8) reported better vision in the eye receiving wavefront-optimized LASIK, and 41.9% (n=13) reported no subjective difference in vision between the two eyes. These differences were not statistically significant (p=0.542).
Conclusions: :
Six months after surgery, patient self-reported visual symptoms were not significantly different in eyes receiving wavefront-guided or wavefront-optimized LASIK by the ALCON system. These symptoms were consistent with the patients’ self-evaluation of their overall vision, which revealed no difference between the two groups. Future evaluations will be performed on this patient cohort at 12 months post-operatively to further evaluate the visual symptoms.
Clinical Trial: :
http://www.clinicaltrials.gov NCT01138189
Keywords: refractive surgery: LASIK • refractive surgery: comparative studies • refractive surgery