March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
Comparison of Methods to Reduce Post-Keratoplasty Astigmatism
Author Affiliations & Notes
  • Matthew Wade
    Gavin Herbert Eye Institute, Irvine, California
  • Roger F. Steinert
    Gavin Herbert Eye Institute, Irvine, California
  • Footnotes
    Commercial Relationships  Matthew Wade, None; Roger F. Steinert, Consultant for AMO (C)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 1497. doi:
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      Matthew Wade, Roger F. Steinert; Comparison of Methods to Reduce Post-Keratoplasty Astigmatism. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1497.

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      © ARVO (1962-2015); The Authors (2016-present)

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To evaluate the results of three different methodologies to correct high amounts of astigmatism after penetrating keratoplasty.


Retrospective analysis of patients with high astigmatism after penetrating keratoplasty who were treated with diamond blade astigmatic keratotomy (AK), femtosecond flap (IntraLase) conventional or wavefront guided LASIK (VISX), or a toric intraocular lens (Alcon). The key outcome measure was manifest cylinder. Enrollment in each type of correction was at the surgeon’s discretion.


A total of 35 eyes were studied. Manifest cylinder was less in the LASIK group than AK or Toric at 1, 3 and 6 months, however none of these differences were significant (Table 1). Mean LogMar uncorrected visual acuity (UCVA) was better with LASIK than AK at 3 months (P=0.01) and 6 months (P=0.002). Likewise, mean UCVA was better with Toric IOL than AK at 1 month (P=0.03), 3 months (P=0.047), and 6 months (P=0.0003).


Femtosecond flap, excimer laser correction or a toric IOL are effective alternatives for reduction of post-keratoplasty astigmatism.  

Keywords: astigmatism • refractive surgery 

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